Current Organic Chemistry - Volume 22, Issue 4, 2018

2-Alkynoates are important unsaturated carbonyl compounds showing a large application as intermediates in organic synthesis. Despite wide importance of these compounds in synthetic chemistry, very few synthetic methods have been reported till date. In recent years much effort has been made to develop the carboxylative coupling of terminal alkynes, organohalides and carbon dioxide to provide the 2-alkynoate deriv Read More

Background: This review updates the field of enantioselective organocatalytic Michael reactions performed in aqueous media, covering the literature since the beginning of 2013. Conclusion: From a green chemistry perspective, this review shows that significant efforts have been recently devoted to the development of these reactions in water and in aqueous media.

Background: For more than one hundred years, it has been known that some 2- isoxazolines can be experimentally obtained by the addition of hydroxylamine or its derivatives to α,β-unsaturated carbonyl compounds. Methodology: General methods for the formation of 2-isoxazolines have not been formulated yet. Conclusion: This review will attempt to summarize the numerous published experimental facts on the addition Read More

Amphiphilic co-networks are a new class of hydrogels that contain both hydrophobic and hydrophilic polymer chains in their structures. So, they have significant properties and great applications in tissue engineering, drug delivery systems, contact lenses, wound dressing, biosensor, and catalyst support. Various strategies have so been developed for the synthesis of amphiphilic co-network, such as ionic or free radical rea Read More

Background: Phenol is one of the toxic and persistent organic pollutants, usually present in industrial wastewaters originated from petrochemical, coal, and olive mill processing industries. Dephenolization of phenol-laden industrial wastewater is a necessary requirement before discharge into open environment. Remediation using microorganisms or bioremediation is well thought-out as one of the sustainable methods for deco Read More

This review describes the chemistry of 1,2,5- and 1,4,5-thiadiazepines. The investigated heterocycles are monocyclic and fused 1,2,5- and 1,4,5-thiadiazepines. The different sections cover: structural elucidation "spectroscopy", reactivity of substituents attached to ring carbon and nitrogen atoms, synthesis of monocyclic and fused heterocycles incorporated 1,2,5- and 1,4,5-thiadiazepine moiety. Nitrogen and sulfur atoms of Read More

Background: Formation of Self-assembled monolayers (SAMs) is one of the most widely used methods to modify a surface to achieve the desired property. It is a very unique, yet simple method to produce highly ordered and stable monolayer on the surface. Adsorption of alkyl thiol to gold or other metal surface is one of the most commonly used methods for the SAM preparation. Biotin is a small molecule used extensively for Read More