Current Organic Chemistry - Volume 22, Issue 21, 2018

This paper presents an overview of known experimental data dealing with the mirror symmetry breaking effect in stochastic reactions (crystallization of NaClO3 from an oversaturated aqueous solution; dissolution-crystallization of the l- and d-NaClO3 crystals mixture under stirring or boiling (Viedma ripening), and similar reactions; Soai reaction of enantioselective autocatalysis and chirality amplification; spontaneo Read More

1,3-Dicarbonyls are widely used in organic reactions. They are able to perform as precursors of pyrimidinones, pyrroles, quinolones, isoquinolines, triazoles and furans et al. Their great success is rooted in the fact that most 1,3-dicarbonyls are commercial (or easy to prepare), stable and versatile. This review will focus mainly on three kinds of reactivity patterns, broadly known as radical, nucleophilic and electrophilic, and Read More

Many biologically active compounds possess 1-sulfonyl pyrrolidine structural motif. Therefore, the development of facile methods for the preparation of these compounds in optically pure form is relevant. One of the regio- and stereoselective approaches to the pyrrolidine derivatives is cycloaddition. Thus, this review article is an attempt to survey literature describing synthetic methods for the preparation of 1-sulfonyl p Read More

With the increasing application and further research of polysaccharides, the development of new green techniques arouses wide attention from academia and industry. Due to special physicochemical properties, ionic liquids (ILs) have been applied widely in carbohydrate chemistry mainly as green and efficient chemical solvents/catalysts for the degradation, synthesis and modification of polysaccharides. Their roles and poten Read More

Titanium tetrachloride has been successfully used in the benzylation of aromatic substrates with a series of benzyl alcohols under mild reaction conditions. With monosubstituted aromatic substrates, ortho and para-substituted products are obtained in almost comparable amounts. With sterically hindered benzyl alcohol derivatives almost exclusively para-substitution occurs.