Current Organic Chemistry - Volume 22, Issue 26, 2018

Although, numerous antimicrobial agents have been reported by the scientists to control fungal and bacterial diseases, but due to less cost effectiveness, non-availability and environmental hazardous of existing antimicrobial agents, there is still a need to synthesize new class of antimicrobial agents to control microbes effectively. Coumarin, a heterocyclic compound containing oxygen in its scaffold, acts as a build Read More

Biaryls are a key structural motif in compounds with various applications, ranging from pharmaceuticals to material science, including ligands for organic synthesis. Given the growing concern about the use of transition metals in organic synthesis in terms of reaction condition mildness, substituents tolerance, reagents costs and toxicity, and purification of the products from metal traces, several alternatives have been d Read More

Heterocycles are cyclic compounds with one or more heteroatom in their structures. They have various pharmaceutical applications. Incorporation of ferrocene scaffold into heterocyclic compounds can change the chemical and physiochemical properties of compounds. Ferrocene derivatives have a significant importance in pharmaceutical sciences like antibacterial, anticancer, antifungal, antiparasitic drug candidates, etc. Mu Read More

Background and Objective: Continuing our research in the field of heterocyclic compounds and exploiting our experience in the synthesis of pyridothieno(furo)[3,2- d]pyrimidine derivatives decorated by suitable reactive groups (in turn able to give rise to the formation of new heterocyclic rings), we now carried out a research with the aim of building in different position of the pyrimidine some new hetero-rings: the 1,3,4-tri Read More

A series of chiral imidazolium salts derived from natural amino acids has been obtained. The synthetic route involves a multicomponent condensation reaction between the corresponding amino acid {(S)-methionine, (S)-threonine, (S)-phenylalanine, (S)- valine and (S)-alanine} in acidic medium and ammonium acetate, glyoxal and formaldehyde in aqueous solution at 95°C to form an imidazole ring in one pot. The Read More