Current Organic Chemistry - Volume 22, Issue 8, 2018

Background: Porous stimuli-responsive polymer membranes are a series of membrane devices with not only common separating and mechanical properties, but also stimuli-responsive capabilities. In recent decades, there is an increasing interest in utilizing track-etch polymer membranes with single or array nanochannels on them as sensing elements in smart responsive membrane devices. Objective: We review the synthesis Read More

Background: Small-angle scattering (SAS) is a powerful technique capable of determining the sample averaged structure of systems within sizes ranging from 1 nm to ~500 nm. This is particularly useful when applied to the study of self-assembled organic systems. Objective: This review article introduces the method of model-dependent analysis of small angle scattering. Method: The underlying mathematical constructs o Read More

Background: Self-diffusion, the random molecular motion of molecules in the absence of a chemical potential, is readily measured with pulsed field gradient NMR techniques. Measurements of diffusion can provide information on chemical binding and porous microstructure. Objective: This manuscript describes the basics of self-diffusion measurement by NMR and provides a justification for the Stejskal-Tanner expression for Read More

In this review, we show the life cycle of parabens, commonly used preservatives that exist in nature and commercial products. Typical synthetic methods to produce parabens, and a set of complimentary characterization techniques to monitor the composition of parabens are also highlighted. This includes solid state analysis using Scanning Electron Microscope (SEM), Differential Scanning Calorimetry (DSC) and X-R Read More

Chemoselective ligation reactions provide facile access to various peptides and proteins including cyclic peptides, post-translationally modified proteins, and peptide/ protein probes. Recently, peptide-ligase-based chemo-enzymatic methods have emerged as promising alternatives to chemical approaches. Ligation mediated by the newly discovered butelase 1 represents one of the state-of-the-art chemo-enzymatic str Read More

Background: Biofilm is a microbial community of microbes that attach to a surface and are enclosed in an extracellular polymeric substance (EPS). Formation of these sessile communities and their inherent resistance to antimicrobial agents are the main reasons for many persistent and chronic infections. Chemotherapy of these infections is unsatisfactory for various reasons including unacceptable toxicity, poor efficacy and dru Read More

Sulfonamides are compounds with a broad spectrum of biological applications, and can act as potential medicinal molecules in drug discovery and drug development. Numerous sulfonamide-based molecules can be used to develop potent lead compounds with better efficacy and less toxicity. This review focuses on the latest information pertaining to sulfonamide derivatives having different pharmacological properties including Read More

Sensor array methodology had attracted much attention because of its advantages in accuracy, diversity and capacities in simultaneous detection and discrimination of multiple analytes. In this study, a colorimetric sensor array comprising chloroauric acid and L-arginine mixture for the detection and identification of iron (II) ion is developed. Principal component analysis and hierarchical cluster analysis showed that the c Read More