Current Organic Chemistry - Volume 22, Issue 16, 2018

Transition metal-catalyzed cross-coupling reactions represent one of the most powerful tools in modern organic chemistry. Due to the relevance of nitrogen heterocyclic compounds for many areas, the development of new and effective methods to afford coupled products from these reagents has become very attractive for organic synthesis. Quinoxaline derivatives encompass one of the most privileged classes of heterocycles, Read More

One of the most valuable principles out of twelve principles of green chemistry is the use of catalysis. The use of serious principles including reducing the utilization or production of hazardous material in chemistry reactions is green chemistry. This paper claims to review the catalytic importance of one of the most important organocatalysts called Ph3P. One of the most successful organocatalysts is phosphine that has Read More

Molecular Imprinting Technology (MIT) is a significant method which can be used to prepare adsorbents with recognition property for target molecules. Those intelligent materials, namely, Molecular Imprinted Polymers (MIPs) are designed with the help of the idea that mimics the matching process of key and lock. Based on the theory of MIPs, Ion-Imprinted Polymers (IIPs) are prepared by using cations or anions as Read More

Acetylcholinesterase (AChE) is well-known enzyme studied in many fields of research, e.g. in Alzheimer's disease, Parkinson's disease, or in eco-toxicology as a biological marker. Many inhibitors of AChE have been identified in nature as well as prepared in chemical labs as a result of systematic synthetic efforts. The organophosphorus (OP) inhibitors of AChE are one of the oldest artificial inhibitors being purposely dev Read More

Novel compounds containing both benzothiazole and azelayl scaffolds were synthesized through Schotten Baumann type reaction between azelayl chloride methyl ester and a series of 2-aminobenzothiazole derivatives bearing different substituents on the aromatic carbocyclic ring. The design of the new hybrids was inspired by their analogy with the structure of some HDAC inhibitors, such as Vorinostat and 9-hydroxystearic aci Read More