Current Organic Chemistry - Volume 22, Issue 14, 2018

The Robinson annulation represents a tandem process including the Michael addition and intramolecular Aldol condensation, affording biscyclo[4.4.0]-1-decen-3-one skeleton with cyclohexanone and methyl vinyl ketone (MVK) being substrates. In this review, the Robinson annulation is summarized by subtitles such as catalysis, the finding of equivalent substrates, and some typical applications in the total synthesis, ai Read More

In recent years, the increased use of antioxidant compounds in food, rubber, plastic, cosmetic and pharmaceutical industries has been encouraged the organic chemists to develop new protocols for the synthesis of antioxidant derivatives. In this review, a brief introduction to six families of organic compounds with antioxidant properties including alkylated phenols, bisphenolic compounds, trisphenols, Xanthenes, Flavanones Read More

The Sonogashira cross-coupling reaction involves the coupling of terminal alkynes with aryl or vinyl halides in the presence of a Pd and a Cu(I) co-catalyst. We tried to reveal the importance of the applications of the Sonogashira reaction in the synthesis of heterocyclic compounds. The reactions occur under relatively mild conditions and tolerate a wide variety of functional groups.

Cation chemosensors have gained more and more attention because they possess an important role in the chemical and biological fields. With the functionalization of cation chemosensors, some special groups were introduced into the skeleton of cation chemosensors. Photoswitchable materials can rearrange reversibly between two different forms in response to light. In recent years, photoswitchable cation chemosens Read More

A continuous-flow procedure was hereby developed and introduced for the synthesis of etherified tryptophol derivatives. It evolved Fischer indolization and condensation in tandem by using Lewis acid as a catalyst. Solvent (alcohol) was considered to participate in the reaction sequence during the step of etherification which is not readily available through traditional approaches. The reaction time of heating and cooling w Read More