Current Organic Chemistry - Volume 22, Issue 19, 2018

Synthesis of aryl nitriles through nanoparticles catalyzed cyanation of aryl halides with K4[Fe(CN)6] as a non-toxic, non-hygroscopic, non-explosive, and inexpensive cyanating agent has drawn great attention in the past several years. This review discussed the recent advances in this interesting and fast-growing research arena. The review is divided into three major sections. The first section will cover Pd-NPs catalyzed reactions. Read More

Background and Objectives: An environmentally benign method for the activation of an alcohol is based on its temporary conversion to a more reactive carbonyl compound by transition metal-catalyzed dehydrogenation. The use of homogeneous complexes in which noble metals were recently replaced by cheap, less toxic, earth-abundant metals (Mn, Fe, Co) enabled sustainable dehydrogenative coupling reactions of al Read More

Racemic and enantioselective synthesis of tetrahydroprotoberberine (THPB) alkaloids, a family of natural products showing a wide range of biological activity, have been based either on extension or enhancement of conventional methods or on new, recently developed tactics. Classical approaches to synthesize the THPB scaffold have utilized Bischler-Napieralski cyclization/reduction or Pictet-Spengler reactions to gener Read More

Carboxylic acids are one type of the most common, readily available and structural diverse synthetic sources which gradually serve as versatile connection points in organic transformations. The decarboxylative reaction of carboxylic acids has attracted great attention in providing an efficient and powerful strategy for the construction of various valuable molecular skeletons. Over the past decades, a number of obvious and sati Read More

Statins are popular drugs widely prescribed in Europe and the USA to control hypercholesterolemia and to prevent cardiovascular diseases. Among these drugs, synthetic statins possess the ability to absorb UV radiations in both UVA and UVB ranges. Light can induce drugs degradation leading to essential changes in their pharmaceutical properties and even to the loss of therapeutic activity, and/or to the formation of deleteriou Read More

A novel, simple and efficient laboratory scale continuous flow protocol has been elaborated for one-pot benzimidazole synthesis via a reductive cyclization method using the commercially available H-Cube Pro. Coupling with a stainless steel microreactor (4mL reactor volume), the acylation of o-nitroaniline was successfully joined in the hydrogenation step without any isolation or purification steps. This concept enabled a fully Read More

Due to error in printing, revised Fig. (4) should be included in the manuscript entitled “Removal of Tetracyclines from Water by Adsorption/ Bioadsorption and Advanced” published in Current Organic Chemistry, 2018, Volume 28, No. 10, page no. 1011.