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Current Organic Chemistry - Online First
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Carbohydrate Derived Value-added Products from Lignocelluloses
Authors: Jyoti, Alisha, Mangat Singh, Pooja Negi, Pratibha Dwivedi and Bhuwan B. MishraAvailable online: 04 October 2024More LessChemistry is confronted with the pressing issues of depleting non-renewable fossil resources and the imperative to combat environmental pollution, which is crucial for a sustainable future. Biomass stands out as the sole organic carbon source in nature among the array of sustainable resources available, positioning it as a prime substitute for fossil-derived chemicals and fuels. Extensive research has been conducted on the abundant lignocelluloses as a potential source for biofuels, bioenergy, and various valuable products, wherein, the incorporation of various processes in biomass fractionation to separate biopolymers (such as lignin, cellulose, and hemicellulose) has the potential to enhance the overall value of the process. However, industrial demonstration of biomass utilization for commercial products has been limited due to the challenges posed by the recalcitrance and complexity of biomass. Therefore, there is a need for efficient reaction processes to enable the production of bio-chemicals and fuels from renewable lignocellulose. This review focuses on the latest chemical methods developed for producing value-added chemicals from biomass-derived cellulose as a renewable feedstock.
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State-of-Art on the Synthesis of Heterocyclic Compounds Targeting SARS-CoV-2
Available online: 25 September 2024More LessThe Corona Virus Disease-19 (COVID-19) pandemic challenged the scientific community in the search for developing effective treatments, such as medicine and/or a vaccine candidate. The SARS-CoV-2 virus and its variants, Omega, Omicron, and Delta, remain as a major threat to human health, causing significant morbidity and mortality worldwide. Given that computational methods are thought to be quick, easy, and inexpensive, they have been widely used in this scenario to design new anti-COVID-19 drug candidates. In addition, heterocyclic scaffolds have been explored exhaustively for their biological properties and as fruitful sources of new molecular entities to fulfill the chemical space available.In light of this, we intend to highlight the synthetic techniques used to produce novel heterocyclic derivatives that may serve as effective anti-COVID-19 lead candidates by focusing on important viral proteins and using computational tools. Then, the objective of this article, with a theoretical nature, is to contribute to the delimitation of organic chemistry methods to achieve new anti-COVID-19 agents.
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