Current Organic Chemistry - Volume 22, Issue 1, 2018

Background: In recent years, there has been a growing interest in the environmental relevance of the presence of several pharmaceutical compounds and their metabolites in water. To avoid further accumulation of these compounds and their metabolites in the aquatic environment, several research groups are investigating chemical and photochemical methods that could be applied in their destruction and subseque Read More

Heliannuols are a unique class of Benzoxacyclic Allelopathic Sesquiterpenes obtained from sunflowers. Allelopathy has been a keen point of interest for researchers and represents a novel but unexplored “Methodology of self-defense mechanism”. Heliannuols exhibit a varied structural pattern of five to eight fused benzoxacycles. Isolation as well as synthesis of eleven members of this group namely heliannuol A to heliannuol L has Read More

Background and Methods: Ratiometric fluorescent probes can provide more precise measurement results than intensity-based fluorescent probes. Carbon dots are convenient platforms to construct ratiometric fluorescent probes. Carbon dots-based ratiometric fluorescent probes can be constructed by carbon dots and other fluorophores' simple mixing or by connecting them via covalent bonds or non-covalent bonds. Oth Read More

Background: Microwave irradiation has emerged as a useful synthetic strategy for chemists and drug developers due to enhanced yields, regioselectivity, and faster reaction times. One area of importance in its practice has been the design of spiro compounds, which possess great interest on account of their natural occurrence and medicinal capabilities. The increasingly large number of these scaffolds and unlimite Read More

Background: Azole-fused pyrimidinones have been synthesized and tested for biological activities. The present copper-catalyzed version will be attempted as an alternative synthetic method for such N-fused hybrid structures. Objective: This research aims to develop a new synthetic method of azole-fused pyrimidinones from β-bromo-α,β-unsaturated amides and azoles (benzimidazole, imidazole and pyrazole). Method: β-Bro Read More

Background: Molybdophosphoric acid (PMo) is used in heterogeneous catalysis. The incorporation of vanadium in the primary structure and a transition metal in the secondary structure of PMo improves the oxidative and acidity capacity. 4- Dihydropyrimidin-2-(1H)-thiones/-ones (DHPMs) derivatives are relevant because of their biological activities. The development of ecofriendly procedures, such as multicomponent reac Read More