Chemistry
Formation of Hydroxyl Radicals in Advanced Oxidation Processes for the Degradation of Contaminated Organic Matter
Jun 2025
Article
Source:
Current Green Chemistry
12,
pp 117
- 137
(2025)
Organic compounds in different solutions have caused several pollution problems to the environment and even affected human health. Advanced Oxidation Processes (AOPs) have been effectively used in the decontamination of these types of compounds. Distinct reactive oxygen species (ROS) have been proposed to explain the degradation or mineralization of contaminating organic matter. ROS such as free radicals (e.g. .OH) superoxide (e.g. .O2− Read More
A Review of Electrochemical Synthesis and Transformations of Small Organic Molecules: Sulfoximines, Isoxazolines, and Benzimidazoles
Jun 2025
Article
Source:
Current Green Chemistry
12,
pp 85
- 116
(2025)
In the realm of synthetic organic chemistry the environmentally friendly manipulation of small organic molecules has gained prominence. One particularly promising approach is electrochemical synthesis which offers a green and sustainable alternative to using hazardous and toxic redox reagents. By harnessing electric current from renewable sources like sunlight or wind electrochemical synthesis emerges as a viable replacement for conventional method Read More
Nano-resolutions for Environmental Salvation: Leaping to Sustainability
Jun 2025
Article
Source:
Current Green Chemistry
12,
pp 146
- 158
(2025)
Nanoparticles have emerged as a transformative technology in environmental remediation addressing the pressing challenges of pollution across air water and soil. Nanoparticles particularly metal oxides carbon-based materials and polymers demonstrate remarkable capabilities in addressing water air and soil contamination. Their high surface area to volume ratio enhances their efficiency in pollutant removal while minimizing toxicity making them suitab Read More
Innovative Techniques for Pharmaceutical Waste Management: Enhancing Drug Recovery and Environmental Sustainability
Jun 2025
Article
Source:
Current Green Chemistry
12,
pp 138
- 145
(2025)
The pharmaceutical sector is a major component of current healthcare manufacturing and distributing drugs biological substances and medical equipment. Despite its advantages the sector creates enormous waste including materials for packaging production by-products expired or unused drugs and other residues creating health and environmental issues. Appropriate pharmaceutical waste handling and medication recovery strategies are vital for li Read More
Microwave-assisted Synthesis of Benzimidazole Derivatives: A Green and Effective Approach
Jun 2025
Article
Source:
Current Green Chemistry
12,
pp 159
- 165
(2025)
IntroductionBenzimidazole derivatives hold a crucial place in medicinal chemistry due to their wide-ranging therapeutic applications. However traditional synthesis methods having inefficiencies such as the need for catalysts and prolonged reaction times in addition to being environmentally unfriendly. This has necessitated the development of alternative synthetic methodologies that are more efficient and eco-friendly.ObjectiveTo establish a novel efficien Read More
Research Progress in Chemical Synthesis and Biosynthesis of Bioactive Imidazole Alkaloids
Jun 2025
Article
Source:
Mini-Reviews in Organic Chemistry
22,
pp 427
- 446
(2025)
The imidazole ring is a five membered ring with a simple chemical structure and is widely present in natural products. Due to its unique chemical structure it is beneficial for the imidazole ring to bind with other functional groups thus exhibiting a wide range of biological activities. The synthesis of imidazole derivatives often involves the Debus method Michael addition method and the use of existing materials to synthesize target compounds through o Read More
A Review on Synthesis, Characterization, and Pharmacological Properties of Some Sydnone Derivatives
Jun 2025
Article
Source:
Mini-Reviews in Organic Chemistry
22,
pp 359
- 380
(2025)
The mesoionic compounds have great importance due to their dipolar nature. They are versatile synthons in synthetic chemistry and possess various chemotherapeutic activity. The most important moiety found in mesoionic compounds is the sydnone ring system. Sydnone derivatives have stimulated much interest among synthetic researchers as a result of their unique dipolar mesoionic character. This ring system is also associated with a wide variet Read More
A Systematic Review of Electrochemical Sensing Devices Based on Metal-organic Frameworks for the Identification of Tumor Biomarkers
Jun 2025
Article
Source:
Mini-Reviews in Organic Chemistry
22,
pp 447
- 462
(2025)
BackgroundElectrochemical sensors have attracted enormous interest in recent decades due to their relatively simple synthesis process the possibility of modifications in their composition and their wide application in detecting analytes.MethodsTo achieve excellent performance materials used in its construction must facilitate the transfer of electrons and provide a large surface area and excellent electrocatalytic activity. Because they are fun Read More
Research Progress on Compounds with Antioxidant Activity Derived from Microorganisms
Jun 2025
Article
Source:
Mini-Reviews in Organic Chemistry
22,
pp 381
- 399
(2025)
Microbial derivatives are a significant source of antioxidants with varying structures leading to different activities due to distinct structure-activity relationships. These structures include polyketones alkaloids terpenes and fatty acids. Microbial-derived antioxidants offer unique advantages such as diversity high yield customizability sustainability and biocompatibility making them promising for various applications. This review aims to address Read More
An Attractive and Comprehensive Review on C-O Bond Formation: Nanomagnetic Recoverable Catalysts to Access Diaryl Ethers via C-O Cross-coupling Reactions
Jun 2025
Article
Source:
Mini-Reviews in Organic Chemistry
22,
pp 411
- 426
(2025)
The simple separation of magnetic nanocatalysts from the reaction mixture using only an external magnet caused a huge revolution in catalysis particularly in organic synthesis. Diaryl ethers compounds containing (Ar-O-Ar linkages) are one of the most important and prominent compounds and are widely found in natural products and pharmaceutical and biological molecules. The C-O cross-coupling or O-arylation reactions of aryl halides with aromatic alcoh Read More
Biochemical Sources of Fulvic Acid and its Application in Agriculture
Jun 2025
Article
Source:
Mini-Reviews in Organic Chemistry
22,
pp 400
- 410
(2025)
The demand for crop yields is increasing in modern society. The challenges to agricultural cultivation nevertheless are posed by soil degradation pollution and the increasing number of extreme weather events due to climate change. All these factors can threaten crop yield and quality. However fulvic acid can effectively alleviate these problems. It’s a type of humus with multiple agricultural values is produced through biomass fermentation and has vario Read More
Recent Advances in the Construction of Coumarin or Quinolin-2-ones Compounds via Radical Cascade Reactions
May 2025
Article
Source:
Mini-Reviews in Organic Chemistry
22,
pp 249
- 262
(2025)
Free radical reactions occupy an important position in synthetic organic chemistry as well as medicinal chemistry significantly complementing and extending the synthesis of coumarin or quinolin-2-one compounds. Moreover the use of constructing coumarin or quinolin-2-one compounds functionalized at the C3 position has certain advantages over traditional noble metal-catalyzed or high-temperature cyclization which is more in line with the advocates of Read More
Synthesis, Reactions and Biological Activity of Pyrimido [5, 4-c] Quinolines based on (Thio)Barbituric Acid and their Analogous (Part IV)
May 2025
Article
Source:
Mini-Reviews in Organic Chemistry
22,
pp 263
- 275
(2025)
Pyrimido [5 4-c] quinolone derivatives are significant synthetic targets that show numerous interesting biological activities. The pyrimido [4 5-b] quinoline is the most famous source of these derivatives which has been used in medicine to antitumor and target different diseases. Since the segregation of quinoline derivatives many synthetic methodologies were advanced for their synthesis. Despite the current interesting findings on this class of pyrimidoquin Read More
Synthesis of Gem-Dimethyl Bicyclic [3.1.0] Proline as an Antiviral Drug Intermediate
May 2025
Article
Source:
Mini-Reviews in Organic Chemistry
22,
pp 276
- 285
(2025)
Gem-dimethyl bicyclic [3.1.0] proline an azadicyclohexane derivative constitutes a prevalent skeleton structure in drugs which serves an important role in the synthesis of antiviral drugs such as Nirmatrelvir Boceprevir Narlaprevir etc. This study offers a comprehensive overview of the documented synthetic strategies for gem-dimethyl bicyclic [3.1.0] proline methyl ester and delves into the application characteristics of each synthetic strategy. These sy Read More
A Comprehensive Review on Synthesis of Thiazoles: Research on Magnetically Recoverable Catalysts
May 2025
Article
Source:
Mini-Reviews in Organic Chemistry
22,
pp 286
- 299
(2025)
In chemistry thiazoles and their derivatives constitute a significant class of biologically active molecules that are thought to be the fundamental building blocks of numerous other biologically active compounds. Many synthetic pharmaceuticals including fungicides dyes antimicrobials and anticonvulsants are made using thiazoles and their derivatives as an intermediary. Thus one of the main areas of organic synthesis research is the presentation of effe Read More
Research Progress on Active Indole Alkaloids in Microorganisms
May 2025
Article
Source:
Mini-Reviews in Organic Chemistry
22,
pp 312
- 339
(2025)
Indole alkaloids are a class of secondary metabolites with a wide range of biological activities. The chemical structure of indole alkaloids is relatively complex but all of them have a remarkable structural feature which is a five-membered pyrrole cyclocyclobenzene ring. Because of the unique structural characteristics of indole alkaloids they have also a wide range of pharmacological activities such as antibacterial anti-inflammatory anti-tumor anti Read More
Recent Routes in Synthesis and Biological Activity of Pyrimido[4,5-b] Quinoline Derivatives: A Review (Part II)
May 2025
Article
Source:
Mini-Reviews in Organic Chemistry
22,
pp 340
- 358
(2025)
The synthesis of organic molecules has been a tremendous and rapid advance in the recent decade to obtain high biological and pharmacological activities. In this review the organic synthesis of pyrimido[45-b]quinoline derivatives is considered an alternative method to traditional procedures for treating many diseases that affect humans. Also by transferring electrons stereoselective syntheses occur via organic reactions in various unnatural and natural Read More
Metal-free Oxidations with m-CPBA: An Octennial Update
May 2025
Article
Source:
Mini-Reviews in Organic Chemistry
22,
pp 300
- 311
(2025)
meta-Chloroperbenzoic acid (mCPBA) is a readily available peroxide that is a powerful oxidizing agent utilized in a range of oxidative reactions. Metal-free oxidations mediated by mCPBA involving selective oxidation of aliphatic amines to oximes selective oxidation of organosulphides/aldehydes synthesis of heterocyclic N-oxides domino C[sp2] hydroxylation/annulation of enaminones (heterocyclic ring formation) acid to phenol conversion oxidation of Read More
Application of Ionic Liquids in Environmental and Food Fields
Apr 2025
Article
Source:
Current Organic Chemistry
29,
pp 642
- 657
(2025)
As a new type of green solvent ionic liquids have made rapid progress in the fields of organic synthesis separation and electrochemistry due to their unique physical and chemical properties. At the same time the new fluorescence characteristics and good separation and adsorption functions of ionic liquids have gradually developed in the field of environment and food showing a good application prospect. Based on the work of our research group and the p Read More
Organocatalytic Stereoselective Synthesis of Dihydrocoumarins
Apr 2025
Article
Source:
Current Organic Chemistry
29,
pp 599
- 620
(2025)
Dihydrocoumarins play pivotal roles as essential components in biologically active molecules drugs and flavor and fragrance compounds. In particular chiral 34-dihydrocoumarins exist in natural products exhibit less toxicity and possess structural diversity and stability. Consequently the asymmetric synthesis of these scaffolds has garnered considerable attention within the chemistry community. Recent advancements have witnessed their synthesis achiev Read More
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