Current Analytical Chemistry - Online First

Background The Iraqi ecosystem, particularly in the southern area, has been polluted due to human activity. Analyzing biological materials is the most common method for detecting the presence of toxic substances in the human body. Method Heavy metal levels of Pb, Ni, and Cd in urine specimens collected from individuals with renal failure and healthy individuals residing in Al-Muthanna province were measured by using Read More

Background 4-n-butylresorcinol (4nBR) was widely used in the treatment of chloasma and skin whitening cosmetics. As a decolorizing agent, it can effectively control the activity of tyrosinase. Market regulatory authorities require truthful labeling of ingredients in cosmetics. Therefore, the quantitative determination of 4nBR is of great practical significance. Hypothesis At present, the main detection method of 4nBR reporte Read More

Introduction Due to the segregation of lightweight aggregate concrete, there is a phenomenon of uneven distribution of ceramsite (aggregate) in commercial ceramsite concrete, lightweight wallboard, which the specific performance of wallboard can reflect. Method In this paper, the non-uniformity of six commercial ceramsite concrete wallboards with different curing conditions was analyzed. Six wallboards were cut into Read More

ObjectivesThis is the first report on the development and validation of thin-layer chromatography (TLC) and high-performance thin-layer chromatography (HPTLC)-densitometric methods for the identification of linoleic acid (LA) in petroleum ether extract (PEE) of Euphorbia neriifolia (EN) stem (ST), latex (LX), and bark (BA).MethodologyChromatographic analyses were performed on silica gel-G and silica gel 60 F254 pl Read More

AimsThis study describes the development of methodologies for the isolation, identification, and quantification of betulinic, oleanolic, and ursolic acids in extracts from Eriope blanchetii (Lamiaceae) and Davilla rugosa (Dilleniaceae).BackgroundBetulinic, oleanolic, and ursolic acids are compounds with biological activities and commercial and technological uses. Developing methodologies for their separation from natura Read More

Surface-Enhanced Raman Scattering (SERS) spectroscopy, as a novel rapid detection technology, offers molecular fingerprinting capabilities that achieve trace-level detection. The key to optimizing SERS sensitivity and reliability lies in the precise control of the nanostructures of SERS substrates. Nature, through billions of years of evolution, has served as a masterful creator, developing organisms with remarkable abili Read More

Microplastics (MPs), as an emerging environmental pollutant, pose a potential threat to ecosystems and human health, and the study of their analytical methods has become particularly important. In this paper, the current research progress of analytical methods for MPs in soil is reviewed. The sources, ecological impacts and possible health risks of MPs are introduced, and the urgency of accurate detection and q Read More

Introduction The recognition of the health hazards of azo dyes has highlighted the need to develop efficient, rapid, and reliable analytical methods for dye determination. Method In this work, electrochemical probing of the azo group of Tartrazine (TZ) and Carmoisine (CR) in food dyes was carried out. Synthesized bismuth and zinc oxide nanoparticles were used to modify Graphite Electrode (GE). Results Electrochemical ana Read More

Analytical Quality by Design (AQbD) represents a transformative methodology in pharmaceutical development, anchored in a systematic, risk-based, and data-driven framework. This approach optimizes analytical methods, fostering heightened product quality, efficient regulatory compliance, and informed decision-making. The industry's increasing acceptance of AQbD principles signifies a paradigm shift towards e Read More

Background In this study, we reported on developing a susceptible, accurate, simple, and economical electrochemical sensor for gabapentin determination in capsules. Methods The ITO electrode was modified with a layer of Prussian blue nanoparticles and then used as the working electrode. Gabapentin was extracted from commercial capsules, and a series of concentrations of gabapentin were prepared for studyi Read More