Respiratory infections are a universal issue with high death rates caused by several pathogens. It makes it obligatory to explore novel antimicrobial drugs to cure lung infections. Phyto-chemicals which are herbal compounds found in plants exhibit antimicrobial properties and contain substances like tannins terpenoids flavonoids etc. Now researchers have opted for novel strategies for drug invention through the screening of medicinal plants. These pl Read More

BackgroundCells generate reactive oxygen species (ROS) which cause oxidative stress. Such stress is counteracted by a complex antioxidant system which includes molecules of the secondary metabolism of plants mainly phenols. Several studies attribute the antioxidant activity of a species to these compounds although in other studies this relationship is not clear.ObjectiveThe aim of this study was to determine whether the amount of total phenols is a go Read More

IntroductionPleurotus citrinopileatus is a natural source of antioxidants and immune system support. Studies have shown that the glucan content in fresh Pleurotus citrinopileatus ranges from 10 to 40% by weight.Methodsβ-glucan is extracted from Pleurotus citrinopileatus mainly by the hydrothermal method. In this study β-glucan was collected from Pleurotus citrinopileatus using an ultrasound-assisted hydrothermal method. Beta-glucan from Vietnam Read More

The imidazole ring is a five membered ring with a simple chemical structure and is widely present in natural products. Due to its unique chemical structure it is beneficial for the imidazole ring to bind with other functional groups thus exhibiting a wide range of biological activities. The synthesis of imidazole derivatives often involves the Debus method Michael addition method and the use of existing materials to synthesize target compounds through o Read More

BackgroundElectrochemical sensors have attracted enormous interest in recent decades due to their relatively simple synthesis process the possibility of modifications in their composition and their wide application in detecting analytes.MethodsTo achieve excellent performance materials used in its construction must facilitate the transfer of electrons and provide a large surface area and excellent electrocatalytic activity. Because they are fun Read More

The simple separation of magnetic nanocatalysts from the reaction mixture using only an external magnet caused a huge revolution in catalysis particularly in organic synthesis. Diaryl ethers compounds containing (Ar-O-Ar linkages) are one of the most important and prominent compounds and are widely found in natural products and pharmaceutical and biological molecules. The C-O cross-coupling or O-arylation reactions of aryl halides with aromatic alcoh Read More

A seizure is the brain's uncontrolled abnormal electrical activity which may result in altered states of consciousness behavior memory or emotion. Seizures start biologically with the activation of susceptible brain neurons which causes synchronized discharges of larger groups of connected neurons. A few potential causes of seizures include medications genetics electrolyte abnormalities sleep state infections brain inflammation and injuries. Medicina Read More

Fibrosis of the liver is the most common pathological feature of many chronic liver diseases progressing to cirrhosis and eventually liver cancer. Currently only individual genes or proteins are targeted by synthetic drugs used to treat liver fibrosis they have limited therapeutic effect and are associated with many side effects. In contrast natural products have shown great advantages and potential in the treatment of liver fibrosis due to their structural divers Read More

An important determinant of population health is the caliber and quality of food that can directly affect the health of the population. Herbs and spices are now the primary ingredients in the global food and nutraceutical industry. Traditional methods for extraction of active metabolites of herbs and spices may lead to lowered extraction efficiency due to high solvent consumption and a longer extraction period. These issues can be resolved by the use of n Read More

Free radical reactions occupy an important position in synthetic organic chemistry as well as medicinal chemistry significantly complementing and extending the synthesis of coumarin or quinolin-2-one compounds. Moreover the use of constructing coumarin or quinolin-2-one compounds functionalized at the C3 position has certain advantages over traditional noble metal-catalyzed or high-temperature cyclization which is more in line with the advocates of Read More