Skip to content
2000
  1. Home
  2. A-Z Publications
  3. Natural Products Journal, The
  4. Volume 15, Issue 5
  5. Article
Volume 15, Issue 5
  • ISSN: 2210-3155
  • E-ISSN: 2210-3163

Abstract

Introduction

is a natural source of antioxidants and immune system support. Studies have shown that the glucan content in fresh ranges from 10 to 40% by weight.

Methods

β-glucan is extracted from Pleurotus citrinopileatus mainly by the hydrothermal method. In this study, β-glucan was collected from using an ultrasound-assisted hydrothermal method. Beta-glucan from Vietnam was evaluated through FTIR, UV-Vis, and SEM imaging. The optical absorption maximum of the extract was recorded at a wavelength of 257 nm. The infrared wave bands in the dried product were found to have characteristic functional groups of polysaccharide compounds. The morphology of β-glucan is a fiber with a diameter of 10-15 um.

Results

Bioassays of the antioxidant and immunogenicity of β-glucan from using this technique are feasible.

Conclusion

The study results show the potential of green and economic chemistry methods in extracting β-glucan from .

© 2025 Bentham Science Publishers
Loading

Article metrics loading...

/content/journals/npj/10.2174/0122103155292732240610115317
2024-06-20
2025-03-30

  • From This Site

    /content/journals/npj/10.2174/0122103155292732240610115317
    dcterms_title,dcterms_subject,pub_keyword
    -contentType:Contributor -contentType:Concept -contentType:Institution
    10
    5
Loading full text...

Full text loading...

References

  1. ParmastoE. Pleurotus citrinopileatus, one of the favourites.Mycologist19871310610710.1016/S0269‑915X(87)80076‑9
     [Google Scholar]
  2. LeeY-L. HuangG.W. LiangZ.C. MauJ.L. Antioxidant properties of three extracts from Pleurotus citrinopileatus.Lebensm. Wiss. Technol.200740582383310.1016/j.lwt.2006.04.002
     [Google Scholar]
  3. HuS.H. WangJ.C. LienJ.L. LiawE.T. LeeM.Y. Antihyperglycemic effect of polysaccharide from fermented broth of Pleurotus citrinopileatus.Appl. Microbiol. Biotechnol.200670110711310.1007/s00253‑005‑0043‑516001252
     [Google Scholar]
  4. HuS.H. LiangZ.C. ChiaY.C. LienJ.L. ChenK.S. LeeM.Y. WangJ.C. Antihyperlipidemic and antioxidant effects of extracts from Pleurotus citrinopileatus.J. Agric. Food Chem.20065462103211010.1021/jf052890d16536582
     [Google Scholar]
  5. ShengY. ZhaoC. ZhengS. MeiX. HuangK. WangG. HeX. Anti‐obesity and hypolipidemic effect of water extract from Pleurotus citrinopileatus in C57 BL /6J mice.Food Sci. Nutr.2019741295130110.1002/fsn3.96231024702
     [Google Scholar]
  6. MukhopadhyayS.B. Cultivation of Pleurotus citrinopileatus on water hyacinth and effect of dietary Pleurotus mushroom on lowering of blood glucose and cholesterol in diabetic model rats.J. Mycopathol. Res.2023613385390
     [Google Scholar]
  7. LinQ. SiY. ZhouF. HaoW. ZhangP. JiangP. ChaR. Advances in polysaccharides for probiotic delivery: Properties, methods, and applications.Carbohydr. Polym.202432312141410.1016/j.carbpol.2023.12141437940247
     [Google Scholar]
  8. GaoY. TanJ. SangY. TangJ. CaiX. XueH. Preparation, structure, and biological activities of the polysaccharides from fruits and vegetables: A review.Food Biosci.20235410290910.1016/j.fbio.2023.102909
     [Google Scholar]
  9. SongJ. KimS. ParkJ. ParkY. KimH.S. Comparison of two β-D-glucan assays for detecting invasive fungal diseases in immunocompromised patients.Diagn. Microbiol. Infect. Dis.2021101111541510.1016/j.diagmicrobio.2021.11541534082306
     [Google Scholar]
  10. YuanC. HuR. HeL. HuJ. LiuH. Extraction and prebiotic potential of β-glucan from highland barley and its application in probiotic microcapsules.Food Hydrocoll.202313910852010.1016/j.foodhyd.2023.108520
     [Google Scholar]
  11. LaitinenM. Mäkelä-SalmiN. MainaN.H. Gelation of cereal β-glucan after partial dissolution at physiological temperature: Effect of molecular structure.Food Hydrocoll.202314110872210.1016/j.foodhyd.2023.108722
     [Google Scholar]
  12. MurphyE.J. RezoagliE. CollinsC. SahaS.K. MajorI. MurrayP. Sustainable production and pharmaceutical applications of β-glucan from microbial sources.Microbiol. Res.202327412742410.1016/j.micres.2023.12742437301079
     [Google Scholar]
  13. ZhangH. WangZ. WangS. ZhangJ. QiuL. ChenJ. Aminated yeast β-D-glucan for macrophage-targeted delivery of CpG oligodeoxynucleotides and synergistically enhanced cancer immunotherapy.Int. J. Biol. Macromol.2023253Pt 312699810.1016/j.ijbiomac.2023.12699837729981
     [Google Scholar]
  14. dos SantosM.C. da SilvaK.F. BastosA.P.A. FélixA.P. de OliveiraS.G. MaiorkaA. Effect of yeast extracted β-glucans on the immune response and reproductive performance of gilts in the adaptation, gestation, and lactation periods.Livest. Sci.202327510528910.1016/j.livsci.2023.105289
     [Google Scholar]
  15. YuanH. HeY. ZhangH. MaX. Ultrasound-assisted enzymatic hydrolysis of yeast β-glucan catalyzed by β-glucanase: Chemical and microstructural analysis.Ultrason. Sonochem.20228610601210.1016/j.ultsonch.2022.10601235594691
     [Google Scholar]
  16. BassartP.Z. FabraM.J. AbadM.A. RubioL.A. Compositional differences of β-glucan-rich extracts from three relevant mushrooms obtained through a sequential extraction protocol.Food Chem.202340213420710.1016/j.foodchem.2022.13420736126575
     [Google Scholar]
  17. FurutaA. IkegamiM. YaguchiT. ItoH. TanakaK. NishinariK. NittaY. Transparent thermoreversible gels of β-(1 → 6)-branched β-(1 → 3)-glucan derived from the cauliflower mushroom Sparassis crispa. Food Hydrocoll.202314210876610.1016/j.foodhyd.2023.108766
     [Google Scholar]
  18. SakdasriW. ArnutpongchaiP. PhonsavatS. BumrungthaichaichanE. SawangkeawR. Pressurized hot water extraction of crude polysaccharides, β-glucan, and phenolic compounds from dried gray oyster mushroom.Lebensm. Wiss. Technol.202216811389510.1016/j.lwt.2022.113895
     [Google Scholar]
  19. KozarskiM. KlausA. van GriensvenL. JakovljevicD. TodorovicN. Wan-MohtarW.A.A.Q.I. VundukJ. Mushroom β-glucan and polyphenol formulations as natural immunity boosters and balancers: Nature of the application.Food Sci. Hum. Wellness202312237839610.1016/j.fshw.2022.07.040
     [Google Scholar]
  20. ShaheenT.I. HussienG.M.A. MekaweyA.A. GhaliaH.H.A. youssryA.A. El MokademM.T. Facile extraction of nanosized β-glucans from edible mushrooms and their antitumor activities.J. Food Compos. Anal.202211110460710.1016/j.jfca.2022.104607
     [Google Scholar]
  21. MishraV. TripathiV. YadavP. SinghM.P. Beta glucan as an immune stimulant in tumor microenvironment — Insight into lessons and promises from past decade.Int. J. Biol. Macromol.202323412361710.1016/j.ijbiomac.2023.12361736758755
     [Google Scholar]
  22. MurphyE.J. MastersonC. RezoagliE. O’TooleD. MajorI. StackG.D. LynchM. LaffeyJ.G. RowanN.J. β-Glucan extracts from the same edible shiitake mushroom Lentinus edodes produce differential in-vitro immunomodulatory and pulmonary cytoprotective effects — Implications for coronavirus disease (COVID-19) immunotherapies.Sci. Total Environ.202073213933010.1016/j.scitotenv.2020.13933032413619
     [Google Scholar]
  23. LiY. LiC. Muhammad AqeelS. WangY. ZhangQ. MaJ. ZhouJ. LiJ. DuG. LiuS. Enhanced expression of xylanase in Aspergillus niger enabling a two-step enzymatic pathway for extracting β-glucan from oat bran.Bioresour. Technol.202337712896210.1016/j.biortech.2023.12896236966944
     [Google Scholar]
  24. Gil-RamírezA. SmiderleF.R. MoralesD. IacominiM. RivasS.C. Strengths and weaknesses of the aniline-blue method used to test mushroom (1→3)-β-d-glucans obtained by microwave-assisted extractions.Carbohydr. Polym.201921713514310.1016/j.carbpol.2019.04.05131079669
     [Google Scholar]
  25. MachmudahS. WahyudionoT. AdschiriT. GotoM. Hydrothermal extraction and micronization in a one-step process for enhancement of β–glucan concentrate at subcritical water conditions.S. Afr. J. Chem. Eng.202346728710.1016/j.sajce.2023.07.009
     [Google Scholar]
  26. SariM. PrangeA. LelleyJ.I. HambitzerR. Screening of beta-glucan contents in commercially cultivated and wild growing mushrooms.Food Chem.2017216455110.1016/j.foodchem.2016.08.01027596390
     [Google Scholar]
  27. BachF. HelmC.V. BellettiniM.B. MacielG.M. HaminiukC.W.I. Edible mushrooms: A potential source of essential amino acids, glucans and minerals.Int. J. Food Sci. Technol.201752112382239210.1111/ijfs.13522
     [Google Scholar]
  28. KoutrotsiosG. TagkouliD. BekiarisG. KalioraA. TsiakaT. TsiantasK. ChatzipavlidisI. ZoumpoulakisP. KalogeropoulosN. ZervakisG.I. Enhancing the nutritional and functional properties of Pleurotus citrinopileatus mushrooms through the exploitation of winery and olive mill wastes.Food Chem.202237013102210.1016/j.foodchem.2021.13102234520973
     [Google Scholar]
  29. BassartP.Z. BäuerlC. FabraM.J. AbadM.A. ColladoM.C. RubioL.A. Composition, structural properties and immunomodulatory activity of several aqueous Pleurotus β-glucan-rich extracts.Int. J. Biol. Macromol.2023253Pt 612725510.1016/j.ijbiomac.2023.12725537827398
     [Google Scholar]
  30. ChewS.K. TeohW.H. HongS.L. YusoffR. Rutin extraction from female Carica papaya Linn. using ultrasound and microwave-assisted extractive methods: Optimization and extraction efficiencies.Heliyon2023910e2026010.1016/j.heliyon.2023.e2026037810831
     [Google Scholar]
  31. KangJ. ShaX.X. GengC.J. LiL.X. ChenJ. RenF.C. TianM.L. Ultrasound-assisted extraction and characterization of Penthorum chinense polysaccharide with anti-inflammatory effects.Ultrason. Sonochem.20239910659310.1016/j.ultsonch.2023.10659337696214
     [Google Scholar]
  32. SoufiO. HarouneM.L. BachirbeyM. AdrarM.S. IdirF. HeddadT. OuldsaadiL. RomeroC. MadaniK. BoulekbacheM.L. Statistical optimization of ultrasound-assisted extraction of polyphenols from olive pomace.Sustain. Chem. Pharm.20233610126010.1016/j.scp.2023.101260
     [Google Scholar]
  33. AbramovičH. GrobinB. UlrihP.N. CigićB. The methodology applied in DPPH, ABTS and folin-ciocalteau assays has a large influence on the determined antioxidant potential.Acta Chim. Slov.201764249149910.17344/acsi.2017.340828621381
     [Google Scholar]
  34. BadmusJ.A. AdedosuT.O. FatokiJ.O. AdegbiteV.A. AdaramoyeO.A. OdunolaO.A. Lipid peroxidation inhibition and antiradical activities of some leaf fractions of Mangifera indica.Acta Pol. Pharm.2011681232921485698
     [Google Scholar]
  35. HodgesD.M. DeLongJ.M. ForneyC.F. PrangeR.K. Improving the thiobarbituric acid-reactive-substances assay for estimating lipid peroxidation in plant tissues containing anthocyanin and other interfering compounds.Planta1999207460461110.1007/s004250050524
     [Google Scholar]
  36. MosmannT. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays.J. Immunol. Methods1983651-2556310.1016/0022‑1759(83)90303‑46606682
     [Google Scholar]
  37. ChenC. MengY. LiS. WuW. LiuC. XuX. ZhangL. Single chain morphology and nanofiber-like aggregates of branched β-(1→3)- d -glucan in water/dimethylsulfoxide solution.Carbohydr. Polym.201613728729410.1016/j.carbpol.2015.10.09026686132
     [Google Scholar]
  38. MaH. HuangQ. RenJ. ZhengZ. XiaoY. Structure characteristics, solution properties and morphology of oxidized yeast β-glucans derived from controlled TEMPO-mediated oxidation.Carbohydr. Polym.202025011692410.1016/j.carbpol.2020.11692433049838
     [Google Scholar]
  39. CaoH. WangX. ShiM. GuanX. ZhangC. WangY. QiaoL. SongH. ZhangY. Influence of physicochemical changes and aggregation behavior induced by ultrasound irradiation on the antioxidant effect of highland barley β-glucan.Food Chem. X20231910079310.1016/j.fochx.2023.10079337780315
     [Google Scholar]
  40. HuT. CaiW. CaiW. ZhengZ. XiaoY. HuangQ. Structure, size and aggregated morphology of a β-D-glucan from Lignosus rhinocerotis as affected by ultrasound.Carbohydr. Polym.202126911834410.1016/j.carbpol.2021.11834434294351
     [Google Scholar]
  41. ChenP-H. WengY-M. YuZ-R. KooM. WangB-J. Extraction temperature affects the activities of antioxidation, carbohydrate-digestion enzymes, and angiotensin-converting enzyme of Pleurotus citrinopileatus extract.Yao Wu Shi Pin Fen Xi201624354855528911560
     [Google Scholar]
/content/journals/npj/10.2174/0122103155292732240610115317
Loading
Ultrasound-assisted Extraction of Β-glucan from Vietnam Pleurotus Citrinopileatus Enhances Anti-oxidant Activities
Natural Products Journal, The 15, E200624231105 (2025); https://doi.org/10.2174/0122103155292732240610115317
/content/journals/npj/10.2174/0122103155292732240610115317
/content/journals/npj/10.2174/0122103155292732240610115317
Loading

Data & Media loading...

Supplements

Supplementary material is available on the publisher's website along with the published article.

file format download Download

  • Article Type:     Research Article
Keyword(s): antioxidant; immunogenicity; Pleurotus citrinopileatus; ultrasound-assisted; β-glucan

Most Cited Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test