Current Organic Chemistry - Volume 27, Issue 6, 2023

The design and synthesis of an efficient Ni-MgO solid solution catalyst with specific morphology for the hydrogenation of nitroarenes is highly required. In this work, a banana- like Ni-MgO solid solution incorporation of carbon catalyst (termed as Ni/MgO-C) has been synthesized via a MOFs-templating strategy for one-step pyrolysis of bimetallic Ni- Mg@MOFs. The developed Ni/MgO-C catalyst was applied to the hydrogenatio Read More

Nitrogen heterocycles represent one of the most important units in modern organic chemistry besides their wide existence broadly in natural products, pharmaceuticals, and functional materials. Among these heterocycles, pyrazole, the molecule of the present work, received much attention in organic synthesis because it delivers significant therapeutic and biological values as it was found to be the core unit of many Read More

This review summarized and systematized the currently known methods of substituting phenolic fragments of calix[4]arenes in the para-position, mainly focusing on the conditions of regioselective carrying out such processes. The reactions of the further transformation of the inserted functional groups, which allows the expansion of the family of para-substituted calixarenes, are also considered. These reactions can be Read More

The use of herbal remedies is more current in illnesses with chronic diseases. One of these important applications is the usage of many plant-derived compounds as cytotoxic agents for the treatment of cancers. Various research has been done on several species of Pulicaria genus for the evaluation of antihistaminic, antimicrobial, antitumor, antiinflammatory, antioxidant, antibacterial, antifungal, insecticide, and leishmani Read More

Here we report the easy synthesis of dendrimer conjugates with four and eight naproxen moieties at the periphery. The synthesis involved two steps protection-deprotection sequence joined with triethylene glycol. A comparison was made between the cytotoxicity of dendron-naproxen conjugates and that of G1.0 G2.0 dendrimer-naproxen conjugates. Cytotoxicity studies showed that dendron conjugates were toxic towa Read More

In the current work, we have utilized the reactivity of N-(4-acetylphenyl)-2-(4- formylphenoxy)acetamide for the synthesis of novel series of 1,2-dihydropyridines, Arylidenes, and hydrazides. Our strategies were prolonged for the synthesis of novel terthienylnicotinamidine hydrochloride salt through a Stille coupling reaction of 6-(5'-bromo- [2,2'-bithiophen]-5-yl)nicotinonitrile with 2-tributyltin thiophene followed by treatment Read More