Current Organic Chemistry - Volume 27, Issue 5, 2023

Transformations of the difunctionalizated cyclodextrin derivatives is a daunting task due to the challenging purification and unambiguous characterization of the final compounds. Lactose has the ability to recognize the liver cells, and the folate receptor (alpha subunit) is overexpressed in multiple tumors, including liver cancer. Therefore, cyclodextrin conjugated with lactose and folic acid should have the liver cell targeti Read More

The indole nucleus is one of the most important ring systems for pharmaceutical development. Various natural products of new molecular structures with diverse biological activities have been reported from marine flora and fauna, thus ensuring motivation in the search for newer natural products. The unique structural features of triindole containing three indole rings and impressive biological activities make these Read More

The photocatalytic conversion of methane (CH4) into methanol (CH3OH) has evoked great interest recently. In this minireview, we summarize the recent advances and current status on how to construct efficient semiconductor-based photocatalysts for enhancing the CH4 conversion efficiency and selectivity to CH3OH. This minireview firstly introduces the different radicals induced photocatalytic CH4 conversion mechanisms. Th Read More

This account reviews synthetic strategies for constructing and transforming CF3S(O) structural moiety developed during the last decades. Existing paths to the synthesis of CF3S(O)-containing organic molecules are demonstrated. Among these are direct trifluoromethanesulfinylation reactions, oxidation of compounds having CF3S function, substitutive trifluoromethylation reactions of sulfinic acid halides and esters, and rearran Read More

Introduction: Herein we report the efficient oxidative transformations of aryl amines to azoarenes and aryl thiols to the corresponding disulfides using diacetoxyiodobenzene and potassium iodide as transition metal-free catalysts in acetonitrile at room temperature. The developed protocols are highly efficient and employ readily accessible, inexpensive, and environmentally friendly starting. Methods: All the reactions were ca Read More

Nature is an inspiring source in drug discovery which constantly reveals new complex chemical structures of natural products that inherit attractive chemical challenges for organic chemists to synthesize them. Taxol is a unique natural product that impressive biological properties and a very tempting chemical structure that motivated organic chemists all over the world to enter the race for synthesizing it. The total synthesis Read More