Current Organic Chemistry - Volume 27, Issue 21, 2023

Deoxycholic and cholic acid-based receptors 6, 13, and 16 containing imidazolium groups were synthesized, and their properties as anion receptors have been evaluated. Cholaphanes 13 and 16 exhibited moderate binding selectivity and affinity for fluoride ions, while cholapod 6 showed low binding selectivity and affinity for chloride ions due to the presence of a nitro group in the imidazolium ring. The H-bonding interactions i Read More

Boesenbergia rotunda (the family Zingiberaceae) is a well-known medicinal plant from Southeast Asia and China. Its parts, especially the roots, were used as an alternative in cuisine, and flavoring. Many attempts tend to explore its phytochemistry and pharmacological values. The ultimate goal of this review is to critically offer the pharmacological values and mechanisms of action of B. rotunda crude extracts and their isola Read More

Tribe Delphineae in the family Ranunculaceae is composed of the genera Aconitum and Delphinium and is a resource plant group with important medicinal value. Alkaloids are the main active ingredients in these two genera, with previous studies primarily focusing on diterpenoid alkaloids. Recent comprehensive studies of the chemical components have uncovered numerous non-diterpenoid alkaloids of diverse structural ty Read More

A topological index is a quantitative measure of molecular structure and connection. It also estimates the toxicological, structural, biological, and physicochemical characteristics of a chemical molecule. The use of nano-structured graphs in the study of chemistry is very extensive. Melem, one of the most significant tri−s−triazine compounds, is a nucleophilic reagent that may be employed in reactions with derivatives of phthali Read More

The synthesis and biological properties of molecules simultaneously comprising various heterocycles, such as fused 2-quinolones and 1,2,3-triazoles, have been evaluated as a part of our ongoing research in medicinal and organic chemistry. We were successful in developing a synthetic procedure for 1,2,3-triazole substituted quinolone derivatives. Infrared, proton, and carbon nuclear magnetic resonance, mass spectros Read More

Warfarin containing a 4-hydroxycoumarin moiety possesses excellent anticoagulant activity, with the (S) enantiomer being the eutomer. The present work is designed to synthesize warfarin based derivatives enantioselectivity to explore their anticoagulant potential. The substituted chalcones were reacted with 4-hydroxycoumarin in the presence of the chiral organocatalyst 9-amino-9-deoxyepiquinine to afford warfa Read More

The activation and thermodynamic parameters of the Diels-Alder reaction of cyclopentadiene, anthracene and tetracene with C60 fullerene are estimated at the DFT level using PBE0, B3LYP and CAM-B3LYP functionals and the effect of accounting for dispersion interactions in various semi-empirical Grimme models on these parameters. Structural characteristics of the reagents, products, pre-reaction van der Waals comple Read More