Current Organic Chemistry - Volume 27, Issue 16, 2023

A relatively new field dubbed "green chemistry" seeks to achieve sustainability at the molecular level. This topic has received a lot of interest in recent years because of its ability to fulfill both environmental and economic goals through non-hazardous chemical innovation. A number of substituted quinoline derivatives were synthesized using microwave irradiation (MW), light irradiation, the presence of a non-biodegrada Read More

Data Science and Machine Learning approaches have recently expanded to accelerate the discovery of new materials, drugs, synthetic substances and automated compound identification. In the field of Organic Chemistry, Machine Learning and Data Science are commonly used to predict biological and physiochemical properties of molecules and are referred to as quantitative structure active relationship (QSAR, for biologi Read More

Imidazole derivatives, which belong to 1,3-diazole family, have two nitrogen atoms at 1 and 3 positions in the aromatic ring. Imidazole derivatives diversely appear both in nature and synthetic sources. Some natural imidazoles play important roles in human life such as histidine, histamine and biotin. Imidazole-based compounds possess a wide range of bioactivities such as those including antimicrobial, anticancer, antiparasitic, Read More

A copper oxide supported on silica (CuO/SiO2) catalyst has been prepared which catalyzes a three-component reaction between 2-aminobenzopenone, benzaldehyde, and ammonium hydroxide leading to a convenient synthesis of 1,2-dihydroquinazoline. The main advantages of the process over the previous reports are room temperature reaction, selective formation of 1,2-dihydroquinazoline as a sole product, a Read More