Current Organic Chemistry - Volume 27, Issue 11, 2023

The plant coriander, family umbelliferae, has applications in both the culinary and traditional medical fields. It has a wide variety of phytochemicals, including polyphenols, vitamins, and many phytosterols. These phytoconstituents are responsible for the pharmacological activities of coriander, which include anticancer, anti-inflammatory, anti-diabetic, and analgesic actions. The following online resources were utilised to conduct Read More

The utility of quinazoline scaffolds as intermediates in new medicinal drug development and discovery has grown in recent decades. The quinazoline framework is a valuable pharmacophore, intermediate, and interesting building block with a wide range of pharmacological activities that has piqued the interest of researchers in developing novel synthetic strategies in medicinal chemistry. In contrast to time-, solvent-, Read More

Recently, levulinic acid as an important bio-based platform compound has attracted wide attention, and its potential application value is very high. This article focuses on chem-catalytic produced ethyl levulinate (EL) from biomass-derived carbohydrates (C6 carbohydrates) via multiple reaction pathways, which has an energy density comparable to gasoline and has great potential as a fuel additive. This review focuses on recent Read More

Heterocyclic compounds containing nitrogen have emerged as crucial entities in the realm of medicinal chemistry. Among these, Schiff bases derived from indole or compounds incorporating an indole moiety have demonstrated a wide range of biological properties, including antibacterial, anticancer, antitumor and antimicrobial activities. The diverse characteristics exhibited by Schiff bases have stimulated the exploration Read More

The synthesis of porphyrins with halogens and nitro groups in meso-aryl rings is described. Halo-substituted meso-tetraarylporphyrin derivatives in the reaction with sodium nitrite in trifluoroacetic acid at 40°C (or room temperature) afford 5-(4-nitroaryl)-10,15,20- triarylporphyrins. The above mono-nitro products bearing halogens on meso-aryl rings (F, Cl, Br) are difficult to obtain selectively. The method elaborated herein allo Read More

A potent, eco-friendly approach for converting 2,6-arylpiperidin-4-ones into their corresponding oximes in the presence of hydroxylamine hydrochloride and catalysed by nanosize sulfated titania (TiO2/SO42-) solid superacid was developed. Sol-gel method was employed to synthesize the catalyst and confirmed standard characterization techniques viz., by FT-IR, XRD, TEM, SEM, and EDS analysis. After adding 0.05 g of Read More

A methodology for synthesizing 1st generation triazole-containing dendrons based on epichlorohydrin with different functional groups was developed using a Cu-catalyzed azide-alkyne cycloaddition reaction (CuAAC) reaction. The proposed methodology uses simple reagents and can serve as a basis for the synthesis of dendrons and dendrimers of higher generations. High reaction yields as well as the cost of starting r Read More