Natural Products Journal, The - Online First

Background Peperomia pellucida is a medicinal and vegetable plant used worldwide, representing a multi-purpose vegetable with applications in the pharmaceutical, food and cosmetic industries. Objective This study evaluated the antioxidant, antibacterial, antifungal, anti-inflammatory, and antidiabetic potential of fractional extracts from P. pellucida plant derived from Can Tho City, Vietnam. Methods Four fractional extracts Read More

The complex etiology of Gouty Arthritis (GA) makes it a multidimensional illness for which there are now no effective therapeutic therapies that can stop its development entirely. This review examines how effectively different plants and their constituents reduce blood uric acid levels and lessen the predisposition to gout. Research has looked at the possible roles of oxidative stress markers, inflammatory pathways, important tran Read More

Breast cancer, a pervasive global malignancy, is anticipated to undergo a significant increase by 2040. Despite the conventional armamentarium of treatments including chemotherapy, radiation therapy, and surgery, the intricate landscape of breast cancer, characterized by its multifaceted surface receptors and signalling pathways, presents formidable challenges to treatment efficacy. Epigallocatechin-3-gallate (EGCG), extr Read More

In this study, we utilized high-performance liquid chromatography coupled with quadrupole-time of flight mass spectrometry (HPLC-Q-TOF/MS/MS), combined with electrospray ionization in the positive mode (ESI+), to establish a comprehensive framework for chromatographic separation and mass spectrometric detection. The primary focus was on performing collision-induced dissociation (CID) experiments on levantilide D, a Read More

The lack of melanin-producing cells in the epidermis causes white patches to develop in vitiligo, a chronic skin disorder. Although vitiligo seldom causes physical injury, it can have serious psychological and social consequences, such as diminished self-confidence and feelings of inadequacy. While there is no known cure for vitiligo, there are several treatments that can help control the illness and lessen its impact on people's l Read More

Background Stemona tuberosa Lour. is a plant belonging to the genus Stemona (Stemonaceae) that has been utilized in traditional Chinese medicine (TCM) for its antitussive and antiparasitic properties. Endophytic fungi have been shown to play an important role in the growth and metabolism of plants. Fermentation involving endophytic fungi tends to result in the production of new or more potent pharmacological Read More

The investigation of computational techniques to forecast the bioactivity of natural substances has been spurred by the growing interest in utilizing their medicinal potential. A branch of artificial intelligence called deep learning has been particularly useful for predicting outcomes in a variety of fields, such as bioactivity prediction and drug discovery, by evaluating large amounts of complex data. An overview of current developm Read More

The present review comprehensively explores an overview of a versatile essential oil from genus Lavandula. Oil finds wide application in the aromatherapy and cosmetic industry. This paper emphasizes the chemical constituents of the oil that are responsible for the diverse therapeutic applications. Various extraction techniques, such as steam distillation, hydro distillation, supercritical liquid extraction and ultrasound ass Read More

Of the several forms of breast cancer, triple-negative breast cancer (TNBC) is the most aggressive, is not responsive to traditional human/hormonal epithelial growth factor receptor 2 (HER2)-targeted therapies because the corresponding receptor targets are absent, TNBC tends to be more invasive in form, metastasis, have an early recurrence rate and develop medication resistance. For TNBC, some of the most popular typ Read More