New Emirates Medical Journal - Volume 5, Issue 1, 2024

Neurodegenerative diseases, characterized by the progressive degeneration of neurons, represent a significant and growing global health concern. Despite extensive research, the underlying molecular mechanisms driving these conditions remain elusive. Enzyme dysregulation has emerged as a pivotal player in the pathogenesis of various neurodegenerative disorders, including Alzheimer's, Parkinson's, and Huntington's diseases. Read More

BackgroundNormal circadian blood pressure response includes a nocturnal fall in BP by 10 to 20% of the average daytime BP. Many diseases, including diabetes mellitus, alter these normal circadian BP changes. DM, through its long-term microvascular and macrovascular complications, such as autonomic neuropathy, affects BP dipping patterns by decreasing dipping (non-dipper), exaggerating dipping (nocturnal hypoten Read More

This review paper aims to investigate the therapeutic benefits of pemirolast across different medical conditions, including asthma, allergic rhinitis, cancer, conjunctivitis, etc. The prevalence of allergic conditions has risen in recent decades, primarily attributed to environmental factors. This paper explores the role of pemirolast in managing and mitigating these diseases, shedding light on its potential applications in the conte Read More

Malaria is a life-threatening disease spread via female Anopheles mosquitoes. Assortments of factors are causing the trouble i.e., (i) fierce opposition posed by the plasmodium life cycle and intracellular localization for pathogens in hepatocytes and erythrocytes; (ii) The decisive physical and chemical properties among most antimalarial drugs, that exhibit an amphiphilic property allowing them to be widely circulated in an Read More

ObjectiveAn adverse drug reaction is defined as “an appreciably harmful or unpleasant reaction, resulting from an intervention related to the use of a medicinal product, which warrants prevention or specific treatment, alteration of the dosage regimen, or withdrawal of the product, as it predicts hazard from future administration.”MethodologyCurrently used to report such responses, the International Classification of Dise Read More

Introduction Osteoporosis is a bone condition that disrupts bone structure, reduces its strength, and increases the risk of fractures. While osteoporosis is commonly recognized as a disorder affecting the elderly, it can also develop in younger adults and be accompanied by other disorders. Screening individuals and diagnosing those at higher risk of osteoporosis early may significantly reduce the likelihood of comp Read More

ObjectiveThe study sought to quantify the frequency and categorize the types of prescribing errors occurring in outpatient settings while evaluating the efficacy of pharmacist interventions in mitigating such errors.MethodologyThis study was a cross-sectional, retrospective interventional study conducted over a one-year period from September 1, 2017, to August 31, 2018, at the outpatient departments of one government and Read More

BackgroundType 2 diabetes is a heterogeneous disease characterized by high blood glucose levels. Its prevalence is increasing as a result of lifestyle, related genes expression, and insufficient insulin signaling. The activation or inhibition of some proteins in the insulin signaling pathway play a vital role in glucose uptake into the cells and in maintaining serum glucose homeostasis. Phosphoinositide-3-kinase (PI3K), 3-phos Read More

Cancer remains one of the most prevalent diseases, with a high mortality rate, despite advancements in technology and science. Patients diagnosed with cancer typically undergo a traumatic experience, enduring both mental anguish and physical exhaustion. Psychosocial distress is common among cancer patients and can have a detrimental effect on their overall quality of life. Therefore, it is crucial for oncology he Read More

This paper describes an innovative tool for formative assessment. This involves designing and implementing a Virtual Escape Room for students of Master’s in Health Professions Education (MHPE) at Gulf Medical University. Escape Room is a type of game-based education where players are constrained in a room, and they must solve a series of interconnected challenges in the form of puzzles or riddles to escape the room. E Read More

IntroductionValvular heart diseases are some of the most common causes of cardiovascular morbidity and mortality worldwide. The mitral valve is estimated to be the cause of 15% of deaths in heart valve disease. Mitral valve dysfunction can be treated with a variety of operative options, one of which is mitral valve replacement. Although it is less desirable than repair, in some situations, it is the only viable option. Thus, we con Read More

BackgroundA lack of proper anti-malarial medication use can lead to drug resistance, failed therapy, and even death. It is unclear how widespread the use of fake anti-malarial medications is in India. Better malaria treatment and the execution of regulatory initiatives to improve anti-malarial drug quality necessitate regional research into the quality of available anti-malarial pharmaceuticals. This study aimed to look into the q Read More

The scope of online assessment in the field of medical education is extensive and varied, encompassing a wide range of types of assessments and purposes. For the assessment of the cognitive domain, online assessment can be carried out with the help of a number of assessment methods. As is the case with any potential tool, even online assessments have their share of limitations, and we must be aware of this as it can help u Read More

BackgroundThe normal anatomy of the coronary arteries consists of the right coronary artery and the left main coronary artery, which originate from the right and left sinuses of Valsalva in the aortic root separately. In general, congenital anomalies of the coronary artery are uncommon in adults. The ectopic origin of a coronary artery from the pulmonary trunk is part of a group of infrequent coronary artery anomalies. The Read More

BackgroundIdentifying the preferred learning modalities of students is crucial for a comprehensive understanding of the content of the study, and this can be achieved by employing the VARK inventory developed by Neil D. Fleming. The preferred learning modality of students significantly influences their learning outcomes.AimThis study aimed to identify the preferred learning modalities among health professional student Read More

BackgroundNowadays, the resistance to available antibiotics could be mentioned as a global threat to public health. The aim of this preliminary study was to conduct a retrospective survey associated with the prevalence of Nosocomial Infections (NIs) and the pattern of microbial resistance in a tertiary care referral hospital (Alzahra), Isfahan, Iran.MethodsThe data between the years 2016 to 2022 were extracted from the off Read More

BackgroundSickle cell anemia (SCA) poses significant metabolic challenges in affected individuals, yet the relationship between resting metabolic rate (RMR) and disease severity remains underexplored, particularly in Sudanese pediatric populations.AimThe aim of this study is to investigate the RMR and its correlation with disease severity scores and treatment with hydroxyurea in Sudanese patients with sickle cell disease.Materi Read More

IntroductionNon-resolving pneumonia after antibiotic treatment is encountered on quite a few occasions in clinical practice and is estimated to account for approximately 15 percent of inpatient pulmonary consultations and 8 percent of bronchoscopies. This is more frequently seen in intensive care/ ventilated patient-associated pneumonia compared to community-acquired pneumonia. Treatment failures are mostly d Read More

BackgroundIn the year 2009, Remdesivir or Veklury was discovered by Gilead Sciences for the management of hepatitis C, Ebola and Marburg virus disease through injection into a vein and then a few years later, 22nd Oct 2020 (United States), the drug was recommended for the management of COVID-19 under a provisional guideline.ObjectiveThe aim of this systematic review was to address pharmacotherapy approaches ass Read More

BackgroundAlthough most cases of choriocarcinoma are of gestational origin, rare cases of extrauterine origin (such as pulmonary) have been reported, which have a poor prognosis.Case PresentationWe present one such rare case involving a 35-year-old female patient who initially presented to the emergency department with hemothorax and was found to have primary lung choriocarcinoma after multiple biopsies. Read More