Skip to content
2000
  1. Home
  2. A-Z Publications
  3. New Emirates Medical Journal
  4. Volume 5, Issue 1
  5. Article
Volume 5, Issue 1
  • ISSN: 0250-6882
  • E-ISSN: 0250-6882
file format pdf download PDF
side by side viewer icon HTML

Abstract

Alternative medication is used for treating the common problems associated with pregnancy. 80% of women suffer from morning sickness during pregnancy. Treatment during pregnancy using non-pharmacological therapy is quite popular all over the world as it is safe and has no negative effects on the fetus. Nausea and vomiting are one of the most prominent problems faced by pregnant women. Acupressure and Aromatherapy have been used by pregnant ladies nowadays for relieving nausea and vomiting symptoms. Conventional therapies also aid in medication of morning sickness in pregnancy duration that covers drugs like Antiemetics, Corticosteroids, Antihistaminic, IV fluids and Vitamin-B6 supplements. Many scientific studies have demonstrated that few drugs that come under conventional treatment cause severe birth defects and stillbirth. This is the leading reason pregnant women prefer to use herbs instead of using conventional medical treatment. The prospective of this review article is to find out the alternative and conventional therapeutic approaches for alleviating the symptoms of morning sickness during pregnancy.

© 2024 The Author(s). Published by Bentham Science Publisher.
This is an open access article distributed under the terms of the Creative Commons Attribution 4.0 International Public License (CC-BY 4.0), a copy of which is available at: https://creativecommons.org/licenses/by/4.0/legalcode. This license permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Loading

Article metrics loading...

/content/journals/nemj/10.2174/0102506882282929231212074538
2023-12-19
2025-01-19

  • From This Site

    /content/journals/nemj/10.2174/0102506882282929231212074538
    dcterms_title,dcterms_subject,pub_keyword
    -contentType:Contributor -contentType:Concept -contentType:Institution
    10
    5
Loading full text...

Full text loading...

/deliver/fulltext/nemj/5/1/NEMJ-5-E02506882282929.html?itemId=/content/journals/nemj/10.2174/0102506882282929231212074538&mimeType=html&fmt=ahah

References

  1. YuY. ChungH.C. HemingwayL. StoffregenT.A. Standing body sway in women with and without morning sickness in pregnancy.Gait Posture201337110310710.1016/j.gaitpost.2012.06.02122824679
     [Google Scholar]
  2. AbdolhosseiniS. Hashem DabaghianF. MehrabaniM. MokaberinejadR. A review of herbal medicines for nausea and vomiting of pregnancy in traditional Persian medicine.Galen Med. J.20176428129010.31661/gmj.v6i4.809
     [Google Scholar]
  3. ElmahdyM. ElmarsafawyA. ElkafashD. Association between helicobacter pylori infection and hyperemesis gravidarum.Int. J. Reprod. Contracept. Obstet. Gynecol.2016593175318010.18203/2320‑1770.ijrcog20163007
     [Google Scholar]
  4. LacasseA. ReyE. FerreiraE. MorinC. BérardA. Epidemiology of nausea and vomiting of pregnancy: Prevalence, severity, determinants, and the importance of race/ethnicity.BMC Pregnancy Childbirth2009912610.1186/1471‑2393‑9‑2619573237
     [Google Scholar]
  5. QuinlaJ.D. HillD.A. Nausea and vomiting of pregnancy.Am. Fam. Physician200368112112812887118
     [Google Scholar]
  6. BraunsteinG.D. HershmanJ.M. Comparison of serum pituitary thyrotropin and chorionic gonadotropin concentrations throughout pregnancy.J. Clin. Endocrinol. Metab.19764261123112610.1210/jcem‑42‑6‑1123932175
     [Google Scholar]
  7. MassonG.M. AnthonyF. ChauE. Serum chorionic gonadotrophin (hCG), schwangerschaftsprotein 1(SP1), progesterone and oestradiol levels in patients with nausea and vomiting in early pregnancy.BJOG198592321121510.1111/j.1471‑0528.1985.tb01084.x3872132
     [Google Scholar]
  8. WalshJ.W. HaslerW.L. NugentC.E. OwyangC. Progesterone and estrogen are potential mediators of gastric slow-wave dysrhythmias in nausea of pregnancy.Am. J. Physiol.19962703 Pt 1G506G5148638718
     [Google Scholar]
  9. GárdiánG. VörösE. JárdánházyT. UngureánA. VécseiL. Wernicke’s encephalopathy induced by hyperemesis gravidarum.Acta Neurol. Scand.199999319619810.1111/j.1600‑0404.1999.tb07344.x10100965
     [Google Scholar]
  10. BroussardC.N. RichterJ.E. Nausea and vomiting of pregnancy.Gastroenterol. Clin. North Am.199827112315110.1016/S0889‑8553(05)70350‑29546087
     [Google Scholar]
  11. HayakawaS. NakajimaN. Karasaki-SuzukiM. YoshinagaH. ArakawaY. SatohK. YamamotoT. Frequent presence of Helicobacter pylori genome in the saliva of patients with hyperemesis gravidarum.Am. J. Perinatol.2000170524324810.1055/s‑2000‑1000511110341
     [Google Scholar]
  12. MitchellA GilboaS WerlerM KelleyK LouikC. National birth defects prevention study. Medication use during pregnancy, with particular focus on prescription drugs: 1976–2008.Am J Obstet Gynecol2011205151.e151.e8
     [Google Scholar]
  13. MaltepeC. Surviving morning sickness successfully: From patient’s perception to rational management.J. Popul. Ther. Clin. Pharmacol.2014213e555e56425654792
     [Google Scholar]
  14. FejzoM.S. MagtiraA. SchoenbergF.P. MacGibbonK. MullinP. RomeroR. TabshK. Antihistamines and other prognostic factors for adverse outcome in hyperemesis gravidarum.Eur. J. Obstet. Gynecol. Reprod. Biol.20131701717610.1016/j.ejogrb.2013.04.01723751910
     [Google Scholar]
  15. MunchS. KorstL.M. HernandezG.D. RomeroR. GoodwinT.M. Health-related quality of life in women with nausea and vomiting of pregnancy: The importance of psychosocial context.J. Perinatol.2011311102010.1038/jp.2010.5420410906
     [Google Scholar]
  16. SharifzadehF. KashanianM. KoohpayehzadehJ. RezaianF. SheikhansariN. EshraghiN. A comparison between the effects of ginger, pyridoxine (vitamin B6) and placebo for the treatment of the first trimester nausea and vomiting of pregnancy (NVP).J. Matern. Fetal Neonatal Med.201831192509251410.1080/14767058.2017.134496528629250
     [Google Scholar]
  17. ChaffeeB.J. TankanowR.M. Ondansetron—the first of a new class of antiemetic agents.Am. J. Health Syst. Pharm.19914871593160910.1093/ajhp/48.7.15931829668
     [Google Scholar]
  18. AvramM.J. SpykerD.A. HenthornT.K. CassellaJ.V. The pharmacokinetics and bioavailability of prochlorperazine delivered as a thermally generated aerosol in a single breath to volunteers.Clin. Pharmacol. Ther.2009851717710.1038/clpt.2008.18418830225
     [Google Scholar]
  19. Park-WyllieL. MazzottaP. PastuszakA. MorettiM.E. BeiqueL. HunnisettL. FriesenM.H. JacobsonS. KasapinovicS. ChangD. Diav-CitrinO. ChitayatD. NulmanI. EinarsonT.R. KorenG. Birth defects after maternal exposure to corticosteroids: Prospective cohort study and meta-analysis of epidemiological studies.Teratology200062638539210.1002/1096‑9926(200012)62:6<385::AID‑TERA5>3.0.CO;2‑Z11091360
     [Google Scholar]
  20. CarmichaelS.L. ShawG.M. MaC. WerlerM.M. RasmussenS.A. LammerE.J. Maternal corticosteroid use and orofacial clefts.Obstet. Anesthes. Dig.2009291121310.1097/01.aoa.0000344674.14744.11
     [Google Scholar]
  21. GurC. Diav-CitrinO. ShechtmanS. ArnonJ. OrnoyA. Pregnancy outcome after first trimester exposure to corticosteroids: A prospective controlled study.Reprod. Toxicol.20041819310110.1016/j.reprotox.2003.10.00715013068
     [Google Scholar]
  22. SoM. BozzoP. InoueM. EinarsonA. Safety of antihistamines during pregnancy and lactation.Can. Fam. Physician201056542742920463270
     [Google Scholar]
  23. BrostB.C. ScardoJ.A. NewmanR.B. Diphenhydramine overdose during pregnancy: Lessons from the past.Am. J. Obstet. Gynecol.199617551376137710.1016/S0002‑9378(96)70059‑58942519
     [Google Scholar]
  24. WattL.O. Oxytocic effects of dimenhydrinate in obstetrics.Can. Med. Assoc. J.1961841053353413783459
     [Google Scholar]
  25. LeathemA.M. Safety and efficacy of antiemetics used to treat nausea and vomiting in pregnancy.Clin. Pharm.1986586606682874910
     [Google Scholar]
  26. DorK. Instant Work-ups: A Clinical Guide to Obstetric and Gynecologic Care E-BookSaunders Elsevier2008
     [Google Scholar]
  27. SahakianV. RouseD. SipesS. RoseN. NiebylJ. Vitamin B6 is effective therapy for nausea and vomiting of pregnancy: A randomized, double-blind placebo-controlled study.Obstet. Gynecol.199178133362047064
     [Google Scholar]
  28. de AloysioD. PenacchioniP. Morning sickness control in early pregnancy by Neiguan point acupressure.Obstet. Gynecol.19928058528541407927
     [Google Scholar]
  29. DhankarS. MujwarS. GargN. ChauhanS. SharmaP. Kumar SharmaS. KamalM.A. RaniD.N. KumarS. SainiM. Artificial intelligence in the management of neurodegenerative disorders.CNS Neurol. Disord. Drug Targets20232311037861051
     [Google Scholar]
  30. WarrenF.Z. Handbook of Medical acupuncture.Van Nostrand Reinhold1976
     [Google Scholar]
  31. VickersA.J. Can acupuncture have specific effects on health? A systematic review of acupuncture antiemesis trials.J. R. Soc. Med.199689630331110.1177/0141076896089006028758186
     [Google Scholar]
  32. DhankharS. ChauhanS. MehtaD.K. Nitika SainiK. SainiM. DasR. GuptaS. GautamV. Novel targets for potential therapeutic use in Diabetes mellitus.Diabetol. Metab. Syndr.20231511710.1186/s13098‑023‑00983‑536782201
     [Google Scholar]
  33. HydeE. Acupressure therapy for morning sickness A controlled clinical trial.J. Nurse Midwifery198934417117810.1016/0091‑2182(89)90077‑32769441
     [Google Scholar]
  34. JoulaeeradN. OzgoliG. HajimehdipoorH. GhasemiE. SalehimoghaddamF. Effect of aromatherapy with peppermint oil on the severity of nausea and vomiting in pregnancy: A single-blind, randomized, placebo-controlled trial.J. Reprod. Infertil.2018191323829850445
     [Google Scholar]
  35. LeeN.M. SahaS. Nausea and vomiting of pregnancy.Gastroenterol. Clin. North Am.2011402309334, vii10.1016/j.gtc.2011.03.00921601782
     [Google Scholar]
  36. MozhganF. MaryamN. BitaJ. ShabnamO. Comparison of ginger with vitamin B6 in relieving nausea and vomiting during pregnancy.Ayu.2013353289293
     [Google Scholar]
  37. HollyerT. BoonH. GeorgousisA. SmithM. EinarsonA. The use of CAM by women suffering from nausea and vomiting during pregnancy.BMC Complement. Altern. Med.200221510.1186/1472‑6882‑2‑512033990
     [Google Scholar]
  38. Saei Ghare NazM. OzgoliG. Effects of complementary medicine on nausea and vomiting in pregnancy: A systematic review.Int. J. Prev. Med.2018917510.4103/ijpvm.IJPVM_430_1630319738
     [Google Scholar]
  39. GhaniR.M.A. IbrahimA.T.A. The effect of aromatherapy inhalation on nausea and vomiting in early pregnancy: A pilot randomized controlled trial.J Nat Sci Res.2013361022
     [Google Scholar]
  40. LawlessJ. The Encyclopedia of essential oils: the complete guide to the use of aromatic oils in aromatherapy, herbalism, health, and well being.Conari Press2013
     [Google Scholar]
  41. FundukianL.J. The Gale encyclopedia of alternative medicine.Gale, Cengage Learning2014
     [Google Scholar]
  42. HeimesK. HaukF. VerspohlE.J. Mode of action of peppermint oil and (‐)‐menthol with respect to 5‐HT 3 receptor subtypes: binding studies, cation uptake by receptor channels and contraction of isolated rat ileum.Phytother. Res.201125570270810.1002/ptr.331621077259
     [Google Scholar]
  43. KimY.J. LeeM.S. YangY.S. HurM.H. Self-aromatherapy massage of the abdomen for the reduction of menstrual pain and anxiety during menstruation in nurses: A placebo-controlled clinical trial.Eur. J. Integr. Med.201133e165e16810.1016/j.eujim.2011.08.007
     [Google Scholar]
  44. PashaH. BehmaneshF. MohsenzadehF. HajahmadiM. MoghadamniaA.A. Study of the effect of mint oil on nausea and vomiting during pregnancy.Iran. Red Crescent Med. J.2012141174474710.5812/ircmj.347723396673
     [Google Scholar]
  45. Yavari kiaP. SafajouF. ShahnaziM. NazemiyehH. The effect of lemon inhalation aromatherapy on nausea and vomiting of pregnancy: A double-blinded, randomized, controlled clinical trial.Iran. Red Crescent Med. J.2014163e1436010.5812/ircmj.1436024829772
     [Google Scholar]
  46. SaberiF. SadatZ. Abedzadeh-KalahroudiM. TaebiM. Acupressure and ginger to relieve nausea and vomiting in pregnancy: A randomized study.Iran. Red Crescent Med. J.201315985486110.5812/ircmj.1298424616799
     [Google Scholar]
  47. PilliteriA. Maternal and child health nursing.6th edPhiladelphiaLipncot. Williams & Wilkins2010
     [Google Scholar]
  48. DvivediJ. DvivediS. MahajanK.K. MittalS. SinghalA. Effect of ‘61-points relaxation technique’ on stress parameters in premenstrual syndrome.Indian J. Physiol. Pharmacol.2008521697618831354
     [Google Scholar]
  49. WiraharjaR.S. HeidyH. RustamS. IskandarM. Kegunaan jahe untuk mengatasi gejala mual dalam kehamilan. Damianus.J. Med.2011103161170
     [Google Scholar]
  50. SulaemanA. MarliyatiS.A. FahrudinM. Antiemetic activity of trigona spp. propolis from three provinces of Indonesia with two methods of extraction.Pharmacogn. J.2018101120122
     [Google Scholar]
  51. JohnL.J. ShantakumariN. Herbal medicines use during pregnancy: A review from the Middle East.Oman Med. J.201530422923610.5001/omj.2015.4826366255
     [Google Scholar]
  52. LaelagoT. Herbal medicine use during pregnancy: Benefits and untoward effects.Herbal Medicineintechopen2018
     [Google Scholar]
  53. OzgoliG. GoliM. SimbarM. Effects of ginger capsules on pregnancy, nausea, and vomiting.J. Altern. Complement. Med.200915324324610.1089/acm.2008.040619250006
     [Google Scholar]
  54. RamadhanuA. Effectiveness of ginger in treating nausea and vomiting of pregnancy.Eureka Herba Indonesia.202231111115
     [Google Scholar]
  55. VutyavanichT. KraisarinT. RuangsriR.A. Ginger for nausea and vomiting in pregnancy: Randomized, double-masked, placebo-controlled trial.Obstet. Gynecol.200197457758210.1097/00006250‑200104000‑0001711275030
     [Google Scholar]
  56. WilkinsonJ.M. What do we know about herbal morning sickness treatments? A literature survey.Midwifery200016322422810.1054/midw.1999.020910970756
     [Google Scholar]
  57. GiacosaA. MorazzoniP. BombardelliE. RivaA. Bianchi PorroG. RondanelliM. Can nausea and vomiting be treated with ginger extract?Eur. Rev. Med. Pharmacol. Sci.20151971291129625912592
     [Google Scholar]
  58. LaneB. CannellaK. BowenC. CopelanD. NteffG. BarnesK. PoudevigneM. LawsonJ. Examination of the effectiveness of peppermint aromatherapy on nausea in women post C-section.J. Holist. Nurs.20123029010410.1177/089801011142341922034523
     [Google Scholar]
  59. ShieldsK.M. Mosby’s Complementary & Alternative Medicine: A Research-Based Approach.SAGE Publications2004
     [Google Scholar]
  60. AhmedM. HwangJ.H. ChoiS. HanD. Safety classification of herbal medicines used among pregnant women in Asian countries: a systematic review.BMC Complement. Altern. Med.201717148910.1186/s12906‑017‑1995‑629137614
     [Google Scholar]
  61. Sarecka-HujarB. Szulc-MusiołB. Herbal medicines—are they effective and safe during pregnancy?Pharmaceutics202214117110.3390/pharmaceutics1401017135057067
     [Google Scholar]
  62. GardinerP. Complementary, holistic, and integrative medicine: chamomile.Pediatr. Rev.2007284e16e1810.1542/pir.28.4.e1617400821
     [Google Scholar]
  63. CuzzolinL. Francini-PesentiF. VerlatoG. JoppiM. BaldelliP. BenoniG. Use of herbal products among 392 Italian pregnant women: Focus on pregnancy outcome.Pharmacoepidemiol. Drug Saf.201019111151115810.1002/pds.204020872924
     [Google Scholar]
  64. MoussallyK. BérardA. Exposure to herbal products during pregnancy and the risk of preterm birth.Eur. J. Obstet. Gynecol. Reprod. Biol.2010150110710810.1016/j.ejogrb.2010.02.00120193976
     [Google Scholar]
  65. RozzaA.L. MoraesT.M. KushimaH. TanimotoA. MarquesM.O.M. BauabT.M. Hiruma-LimaC.A. PellizzonC.H. Gastroprotective mechanisms of Citrus lemon (Rutaceae) essential oil and its majority compounds limonene and β-pinene: Involvement of heat-shock protein-70, vasoactive intestinal peptide, glutathione, sulfhydryl compounds, nitric oxide and prostaglandin E2.Chem. Biol. Interact.20111891-2828910.1016/j.cbi.2010.09.03120934418
     [Google Scholar]
  66. AnderkaM. MitchellA.A. LouikC. WerlerM.M. Hernández-DiazS. RasmussenS.A. Medications used to treat nausea and vomiting of pregnancy and the risk of selected birth defects.Birth Defects Res. A Clin. Mol. Teratol.2012941223010.1002/bdra.2286522102545
     [Google Scholar]
  67. HolstL. HaavikS. NordengH. Raspberry leaf – Should it be recommended to pregnant women?Complement. Ther. Clin. Pract.200915420420810.1016/j.ctcp.2009.05.00319880082
     [Google Scholar]
  68. MittalP. DhankharS. ChauhanS. GargN. BhattacharyaT. AliM. ChaudharyA.A. RudayniH.A. Al-ZharaniM. AhmadW. KhanS.U.D. SinghT.G. MujwarS. A review on natural antioxidants for their role in the treatment of parkinson’s disease.Pharmaceuticals202316790810.3390/ph1607090837513820
     [Google Scholar]
  69. SaharanR. KaurJ. DhankharS. GargN. ChauhanS. KumarS. SharmaH. Hydrogel-based drug delivery system in diabetes management.Pharm. Nanotechnol.20231211110.2174/012211738526627623092806423537818559
     [Google Scholar]
  70. RohillaM. Rishabh BansalS. GargA. DhimanS. DhankharS. SainiM. ChauhanS. AlsubaieN. BatihaG.E.S. AlbezrahN.K.A. SinghT.G. Discussing pathologic mechanisms of Diabetic retinopathy & therapeutic potentials of curcumin and β-glucogallin in the management of Diabetic retinopathy.Biomed. Pharmacother.202316911588110.1016/j.biopha.2023.11588137989030
     [Google Scholar]
  71. HepnerD.L. HarnettM. SegalS. CamannW. BaderA.M. TsenL.C. Herbal medicine use in parturients.Anesth. Analg.200294369069310.1097/00000539‑200203000‑0003911867399
     [Google Scholar]
  72. BealM. Women’s use of complementary and alternative therapies in reproductive health care.J. Nurse Midwifery199843322423410.1016/S0091‑2182(98)00009‑39674352
     [Google Scholar]
  73. FinsterwalderJ. KuppelwieserV.G. Intentionality and transformative services: Wellbeing co-creation and spill-over effects.J. Retailing Consum. Serv.20205210192210.1016/j.jretconser.2019.101922
     [Google Scholar]
  74. BatistaA.L.A. DiógenesA.U.L.R. de SouzaC.R. do NascimentoB.D. MouraB.N. AlvesC.F.J. Clinical efficacy analysis of the mouth rinsing with pomegranate and chamomile plant extracts in the gingival bleeding reduction.Complement. Ther. Clin. Pract.2014201939810.1016/j.ctcp.2013.08.00224439653
     [Google Scholar]
  75. AbdolhosseiniS. Hashem-DabaghianF. MokaberinejadR. SadeghpourO. MehrabaniM. Effects of pomegranate and spearmint syrup on nausea and vomiting during pregnancy: A randomized controlled clinical trial.Iran. Red Crescent Med. J.2017191010.5812/ircmj.13542
     [Google Scholar]
  76. BarnesJ. McLachlanA.J. SherwinC.M.T. EnioutinaE.Y. Herbal medicines: challenges in the modern world. Part 1. Australia and New Zealand.Expert Rev. Clin. Pharmacol.20169790591510.1586/17512433.2016.117171227070431
     [Google Scholar]
  77. TengL. ZuQ. LiG. YuT. JobK.M. YangX. DiL. SherwinC.M.T. EnioutinaE.Y. Herbal medicines: Challenges in the modern world. Part 3. China and Japan.Expert Rev. Clin. Pharmacol.2016991225123310.1080/17512433.2016.119526327232545
     [Google Scholar]
  78. DugouaJ-J. Herbal medicines and pregnancy.J. Popul. Ther. Clin. Pharmacol.2010173e370e37821041871
     [Google Scholar]
  79. Boltman-BinkowskiH. A systematic review: Are herbal and homeopathic remedies used during pregnancy safe?Curationis2016391151410.4102/curationis.v39i1.151427246791
     [Google Scholar]
/content/journals/nemj/10.2174/0102506882282929231212074538
Loading
A Comprehensive Review of Alternative Therapeutic Approaches for Nausea and Vomiting Relief in Pregnancy
NEW Emirates Medical J 5, e02506882282929 (2024); https://doi.org/10.2174/0102506882282929231212074538
/content/journals/nemj/10.2174/0102506882282929231212074538
/content/journals/nemj/10.2174/0102506882282929231212074538
Loading

Data & Media loading...


  • Article Type:     Review Article
Keyword(s): Acupressure; Alternative therapy; Aromatherapy; Conventional therapy; Hcg (human chorionic gonadotropin); Medicinal herbs; Nausea and vomiting

Most Cited Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test