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- Volume 7, Issue 1, 2024
Current Applied Polymer Science - Volume 7, Issue 1, 2024
Volume 7, Issue 1, 2024
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A Comprehensive Review on Transformative Role of Polymer in Advancing Pharmaceutical Drug Delivery System
Authors: Sandesh Bole, Sachin Kothawade, Vaibhav Wagh and Vishal PandeThe present analysis study emphasizes the polymers that are used to deliver therapeutic agents through pharmaceutical drugs. Among such dosage forms are tablets, patches, cassettes, films, semi-solids, and powders. The use of biodegradable polymers is becoming more and more common. They can degrade into non-toxic monomers, and, more significantly, they can be used to make controlled-release devices that Read More
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A Quality By Design (QbD) Prospect in Fabrication of PLGA-based Antipsychotic Long-acting Microspheres: An Alternative to Combination Therapy
Authors: Akanksha Singh, Rajkiran Narkhede and Rajani AthawaleBackgroundDiscontinuation and poor compliance with long-term oral medicine are major therapeutic issues in psychosis treatment. Poorer long-term outcomes may result from non-compliance as well as a higher chance of relapse. In order to sustain therapeutic drug plasma levels, co-administration of oral antipsychotics is necessary for commercially available long-acting injections of second-generation antipsychotics, Read More
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Design, Synthesis, and Evaluation of Lipoyl Ester Conjugated Star PLGA for Sustained Drug Delivery Systems
Authors: Akanksha Singh, Chandan Gupta, Shrikant Godse and Rajani AthawaleBackgroundPoly(lactic-co-glycolic acid) (PLGA), an FDA-approved copolymer, is widely recognized for its biocompatibility, biodegradability, and versatility in drug delivery systems. Despite its advantages, challenges, such as poor drug loading and burst release, motivate the exploration of innovative modifications. The current research aimed to modify the linear PLGA to lipoyl ester terminated star PLGA polymer to minimiz Read More
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- Materials Science and Nanotechnology, Polymer Science, Chemistry, Applied Chemistry, Multidisciplinary Chemistry
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Design, Optimization, and Evaluation of Chitosan-2-mercaptobenzoic Acid as a Dual-functionalized Thiomer
Authors: Tejinder K. Marwaha, Ashwini Madgulkar and Mangesh BhalekarAimsThis study aimed to develop and evaluate mucoadhesive microspheres for the controlled release of zidovudine using a novel dual-functionalized polymer.BackgroundMucoadhesive polymers have recently been widely used to prolong the GI residence time and to modulate the release impact of various mucoadhesive dosage forms. In the present study, a recently synthesized chitosan derivative, chitosa Read More
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