Current Organic Chemistry - Volume 25, Issue 17, 2021

This account reviews some innovative (“non-classical”) synthetic strategies for the formation of CP bonds developed during the last decades. It provides examples of the most important milestones in this field, highlighting the state-of-art of functional phosphoruscontaining molecules. Among these are the direct functionalization of organic substrates through chlorine-free reactions with elemental phosphorus, syntheses based Read More

The development of simple, atom-economical, and sustainable methodologies for the construction of various functional molecules from easily available substrates has been of great interest in synthetic chemistry. N,N-dimethylformamide (DMF) is an inexpensive, abundant solvent and industrial raw material, and it is considered as an effective polar solvent and also as a versatile reagent in synthetic transformations. Du Read More

In nature, flavonoids constitute a relatively diverse family of aromatic molecules such as flavones, flavonols, flavanones, isoflavone, chalcones, and their derivatives. Natural and synthetic flavonoids have reported diverse biological activity including antimycobacterial, antimicrobial, antiproliferative, antiarrhythmic, antiviral, antihypertensive, antioxidant, and anti-inflammatory. Flavonoids have garnered much attentio Read More

Thiophene derivatives, either “small molecules,” oligomers, or polymers, play a role of primary importance among organic semiconductors, therefore, they have numerous and different technological applications in the field of Organic Electronics. For this reason, thiophene-based materials are found in devices, such as Organic Light-Emitting Diodes (OLEDs), Organic Field-Effect Transistors (OFETs), organic solar cell Read More

The study aimed at a novel catalytic eco-friendly one-pot reaction for the synthesis of some new thiosemicarbazone and N-thiocarbamoyl pyrazole derivatives. The prepared and characterized silica-supported zinc chloride (ZnCl2/SiO2) catalyst has been presented for promoting the one-pot reaction between isothiocyanates (1 mmol), hydrazine (1.2 mmol) and 1,3- dicarbonyl (1 mmol) compounds under solvent-free conditio Read More