Current Organic Chemistry - Volume 25, Issue 22, 2021

The 1,3-dipolar Cycloadditions (DCs) of Nitrile Oxides (NOs) have been used as a powerful tool in synthetic organic chemistry. The cycloadducts arising from Cycloadditions (CAs) of NOs to alkenes and alkynes (2-isoxazolines and isoxazoles respectively) are valuable synthetic intermediates because, among others, their capacity to mask other functionalities including α, β -unsaturated ketones, β -hydroxy carbonyl compound Read More

Radical chemistry is known for two centuries. Due to the fascinating nature of the radical-mediated processes, these reactions have attracted the attention of organic chemists to prepare new compounds with diverse stereochemistry. Radical-induced methods mostly follow atom economical principles. Tin-based radical annulation method is the most common and widely used procedure for the synthesis of a wide range of org Read More

2,7-Naphthyridine is one of the six structural isomers of pyridopyridine. Biological investigations have shown that these compounds have a broad spectrum of activity. They have been found to have antitumor, antimicrobial, analgesic and anticonvulsant effects. The broad spectrum of biological activity of 2,7-naphthyridine derivatives is the main reason for the preparation of new compounds containing this scaffold. This review ai Read More

Various diketones such as 1,2-diketones, 1,3-diketones, 1,4-diketones, β - diketones and dicarbonyl compounds are used in the synthesis of core heterocyclic compounds such as pyrazoles, isoxazoles, triazoles and quinolones. They play an important role in synthetic organic chemistry. The diketones and dicarbonyl compounds also act as chelating ligands for the lanthanides and a large number of transition metals in materia Read More

Synthesis of cycloolefin-based polymers via metathesis-accompanied cyclopolymerization and tandem Ring-Opening/Ring-Closing Metathesis (RO/RCM) polymerization are undergoing exciting developments and emerging as an area of great interest in the field of polymer synthesis. Among the conventional polymerization techniques, both cyclopolymerization and tandem polymerization give access to highly functional cycloo Read More