Current Organic Chemistry - Volume 25, Issue 8, 2021

This review collects for the first time enantioselective one-pot processes promoted by green chiral zinc catalysts. It illustrates how much these cheap, non-toxic and environmentally benign catalysts allow unprecedented asymmetric domino and tandem reactions of many types to be achieved, allowing direct access to a wide variety of very complex chiral molecules.

This review deals with the synthetic methods and pharmacological properties of [1,2,3]triazoloquinoline derivatives. There are ten isomers of fused [1,2,3]triazoloquinoline according to the junction between triazole and quinoline. The synthetic methods are subdivided into groups according to the type of isomers. The pharmacological activity of [1,2,3]triazoloquinoline was also reported.

Minisci-type reactions have been widely known as reactions that involve the addition of carbon-centered radicals to basic heteroarenes followed by formal hydrogen atom loss. While the originally developed protocols for radical generation remain in active use today, in recent years, the new array of radical generation strategies have allowed the use of a wider variety of radical precursors that often operate under milder and Read More

In recent years, polyolefin elastomers play an increasingly important role in industry. The late transition metal complex catalysts, especially α-diimine Ni(II) and α-diimine Pd(II) complex catalysts, are popular “chain-walking” catalysts. They can prepare polyolefin with various structures, ranging from linear configuration to highly branched configuration. Combining the “chain-walking” characteristic with different polymeri Read More

An efficient synthesis of 4-arylidene-3-alkylisoxazole-5(4H)-ones has been implemented via the three-component cyclocondensation of aryl(heteroaryl)aldehydes with hydroxylamine hydrochloride and β-ketoesters. The potassium 2,5-dioxoimidazolidin-1-ide has been introduced as the new organocatalyst to facilitate this heterocyclization. In the current process, three starting materials, including substituted benzald Read More