Current Organic Chemistry - Volume 25, Issue 9, 2021

In recent years, supramolecular systems for nano-medicine, and in particular for photodynamic therapy, have gained great attention for their uses as smart and engineered therapeutic agents. We proposed a collection of very recent articles on supramolecular complexes for photodynamic therapy based on different photosensitizers assembled with cyclodextrins, cucurbiturils, calixarenes, pillararenes, or involved in nanobox Read More

The increasing importance of visible light photoredox catalysis as a powerful strategy for the activation of small molecules require the development of new effective radical sources and photocatalysts. The unique properties of organoboron compounds have contributed significantly to the rapid progress of photocatalysis. Since the first work on the topic in 2005, many researchers have appreciated the role of boron-containing co Read More

The present review describes 108 new examples of naturally occurring flavans and flavanones having cytotoxic potential, which have been reported during the period of 2005 to mid-2020. These compounds are found either as aglycones or as glycosides, comprising flavans, flavanones, isoflavanones and miscellaneous flavanones (homo- and bi-flavanones). The main topics addressed in this review are source, structure, Read More

Natural products are the most effective source of potential drug leads. The total synthesis of bioactive natural products plays a crucial role in confirming the hypothetical complex structure of natural products in the laboratory. The total synthesis of rare bioactive natural products is one of the great challenges for the organic synthetic community due to their complex structures, biochemical specificity, and difficult stereoch Read More

The analogs of 6-Amino uracil are essential components due to their biological activities. The uracil is used as an important component for the synthesis of heterocyclic compounds like pyrrolo-, pyrido-, pyrimidine-pyrimido scaffolds. Herein, the application of this compound is reviewed as a precursor in the synthesis of many heterocyclic cores from 2016 to 2020.