Natural Products Journal, The - Volume 15, Issue 2, 2025

Background Actinidia eriantha Benth is a widely used natural product from Traditional Chinese Medicine in the Actinidiaceae family. However, its wild resources have been declining due to over-exploitation. It has become urgent to investigate the genetic diversity for the conservation of A. eriantha, to evaluate the current species and discover strategies for preservation. Methods The internal transcribed spacer (ITS) was us Read More

Background Depression is a mental health disorder with high morbidity and disability rates that has harmful effects on public health worldwide. Despite many hypotheses about its mechanism have been put forward, its deeper mechanism is still unclear. Nowadays, there are many antidepressants developed by pharmaceutical companies, such as fluoxetine, ketamine, and paroxetine used in clinical practice, but the Read More

The medicinal properties of the Cannabis genus are evident and many studies indicate its usefulness to treat many diseases. However, the production of Cannabis-based products has been hampered by its criminalization. Currently its cultivation is not allowed in Brazil, except in specific situations. It increases the price of Cannabis-based products, as it requires the importation of inputs, making it difficult for most of the p Read More

Background Zingiber rubens Roxb., a new species of the Zingiberaceae family, is found profoundly in the Northeastern region of India. It is a rhizomatous geophyte and grows primarily in the seasonally dry tropical biome native to Indo-China regimens. Objective The aim is to research the root part of this plant to discover active constituents and evaluate the molecular mechanism of antidiabetic activity. Methods The hydro Read More

Lung carcinoma is the most ubiquitous and fundamental cause of cancer-related mortality globally. The conventional therapeutic approaches for lung cancer have consistently encountered several challenges and complexities, prompting the exploration of novel tactics for the detection and management of cancer. Lung cancer is a highly preventable disease, and early-stage detection significantly improves patient’s survival r Read More

Objective This review aims to evaluate the latest techniques used in formulating epigallocatechin gallate (EGCG), analyse the difficulties encountered in the process, and offer perspectives on potential future advancements in epigallocatechin gallate formulations for both nutraceutical and pharmaceutical applications. Methods This work provides a thorough literature review and examines current epigallocatechin gallat Read More

Background Hericium erinaceus is a versatile mushroom with potential therapeutic benefits. A variety of bioactive compounds have been found in this mushroom that have anti-ulcer, anti-inflammatory, immunomodulatory, and blood sugar and lipid regulating effects. Objectives The aim is to isolate and characterize compounds from the rice medium of H. erinaceus and evaluate their potential therapeutic effects on oxidative Read More

Across the globe, approximately half of the population diagnosed with diabetes use complementary medicines for the treatment of diabetes. Salacia reticulata (family Hypocrataceae), is an indigenous woody climber flowering plant commonly employed within the Ayurvedic healthcare framework for addressing diabetes and obesity. It is also known as Kothala himbutu and grows in the dry zone forests of India and Sri La Read More

Background Mesophotic coral ecosystems (MCEs) are light-dependent ecosystems found from 30 to 150 m in depth that are highly diverse and relatively understudied worldwide. Methods One new indole alkaloid, chaetoid A (1), one known analog, indigodole B (2), and one known β-carboline type alkaloid 1-acetyl-β-carboline (3), along with three known cyclic depsipeptides, turnagainolide A (4), turnagainolide B (5), arthroamid Read More

Background Anisophyllea disticha (Jack) Baill. (A. disticha) is a species of the Anisophylleaceae family that has undergone the least investigation despite being widely used in folk medicine to cure a wide range of illnesses. Objective The purpose of this study is to examine the impact of various factors on the supercritical fluid extraction of A. disticha in order to maximise recovery of total phenolic content, antioxidant activity, an Read More