Natural Products Journal, The - Volume 15, Issue 4, 2025

IntroductionMilk thistle extract is widely used in dietary supplements due to its strong hepatoprotective effect. There are some differences in the quality characteristics and standard values of milk thistle extract set by pharmacopoeias and standards in various countries and regions.MethodsTo promote the standardization of quality standards for milk thistle extract, this paper summarized and compared the standard characteris Read More

IntroductionMetabolic dysfunction-associated fatty liver disease (MAFLD) is the most common chronic liver disease progressing towards a substantial global health concern. A multitude of therapeutic agents are being used to treat MAFLD. The high prevalence and adverse effects of drugs have increased the global popularity of herbal medicines (HMs) as effective therapeutic agents to treat MAFLD. Among the causes Read More

Fibrosis of the liver is the most common pathological feature of many chronic liver diseases, progressing to cirrhosis and eventually liver cancer. Currently, only individual genes or proteins are targeted by synthetic drugs used to treat liver fibrosis, they have limited therapeutic effect, and are associated with many side effects. In contrast, natural products have shown great advantages and potential in the treatment of liver fibr Read More

A seizure is the brain's uncontrolled, abnormal electrical activity, which may result in altered states of consciousness, behavior, memory, or emotion. Seizures start biologically with the activation of susceptible brain neurons, which causes synchronized discharges of larger groups of connected neurons. A few potential causes of seizures include medications, genetics, electrolyte abnormalities, sleep state, infections, b Read More

An important determinant of population health is the caliber and quality of food that can directly affect the health of the population. Herbs and spices are now the primary ingredients in the global food and nutraceutical industry. Traditional methods for extraction of active metabolites of herbs and spices may lead to lowered extraction efficiency due to high solvent consumption and a longer extraction period. These issue Read More

IntroductionAnacyclus pyrethrum is used in Ayurveda to treat various ailments, ranging from toothache to female infertility. However, the molecular mechanisms of its medicinal properties are obscure and need exploratory studies.MethodsWe aimed to investigate the molecular mechanisms associated with the medicinal properties of A. pyrethrum using zebrafish as an in vivo model. We have employed in silico, i Read More