Current Organic Chemistry - Volume 8, Issue 18, 2004

Carbohydrates contain a high density of functional and stereochemical information in one molecular unit. They have been exploited as enantiopure starting materials in numerous ex-chiral pool syntheses. During the past decade, the potential of carbohydrates in terms of stereodifferentiating auxiliaries has been recognised. Glycosylamines proved to be efficient auxiliaries in stereoselective Strecker syntheses of α-amino nitrile Read More

Self-assembled monolayers (SAMs) of alkane thiols on gold and other metals are versatile constructs with which to study interfacial phenomena and reactions at surfaces. Surface properties of SAMs - e.g., wettability, stability in diverse environments, propensity to interact with or to resist adsorption of macromolecules -- depend on and can be controlled flexibly by the properties of the functional (head) groups in the w posi Read More

At present time the main goal of important research programs is to create new biological and biomimetic materials for asking scientific questions and solving problems relevant to biology, e.g., pharmaceutical development, mutation detection, and DNA sequencing. Widespread approaches to this kind of research are based on design and synthesize structures, and then characterize the physical, structural or biological propertie Read More

Supramolecular complexes can be studied by a variety of spectroscopic methods and substantial information obtained by optical methods, by NMR spectroscopy, and by other techniques, clucidating structure and their stability, are reported in the scientific literature. However, very few data can be found concerning the rates by which these aggregates are formed or dissociated into separate species. This is due to the fact that as Read More

Catalysis by sol-gel doped materials -- chemical conversions mediated by porous glassy matrices containing actives entrapped within their internal huge porosity -- is now a developed chemical technology offering unique advantages in terms of catalyst stability, selective activity and versatility which include ease of materials production and application. In general, the performance of these materials is largely superior compared Read More