Modeling and Synthesis of Conformationally Restricted Amino Acids

At present time the main goal of important research programs is to create new biological and biomimetic materials for asking scientific questions and solving problems relevant to biology, e.g., pharmaceutical development, mutation detection, and DNA sequencing. Widespread approaches to this kind of research are based on design and synthesize structures, and then characterize the physical, structural or biological properties of the new materials. This research involves major experts and scientists in the chemistry of amino acids, peptides, sugars, nucleosides, oligonucleotides, bioconjugation, and particularly conformationally restricted amino acids have been the target of both synthetic and medicinal chemistry, since they can be applied to the design of relevant biologically active compounds.