Current Organic Chemistry - Volume 8, Issue 2, 2004

This review deals with recent progress concerning the preparations, reactions, mechanisms and synthetic applications of some precursor compounds of the fluorine-containing reactive intermediates, such as phenyliodonium bis (perfluoro alkanesulfonyl) methides, PhI+--C(SO2Rf)2; perfluoroalkanesulfonyl azides, RfSO2N3 N,N-dichloro perfluoroalkanesulfonyl amides, RfSO2NCl2, aryldiazonium bis(perfluoro alkanesul Read More

The oxidative activation of arenes is a powerful and versatile synthetic tactic that enables various functionalization of aromatic rings. Central to this chemistry are oxygenated arenes such as hydroxylated arenes or arenols and their simple alkyl ethers whose electron-releasing functions facilitate the oxidation process. These two classes of arenol derivatives can lead to three different types of oxidized intermediates, each of which Read More

This review covers literature on enantioselective synthesis of molecules with substituted quaternary carbon stereocenters from 1992 to 2002. In this overview, we will consider not only the construction of stereocenter itself by generation of carbon-carbon bond or heteroatom-carbon bond, but also other approachs which deal with the preparation of chiral compounds having this type of stereocenters, such as resolution or e Read More

Synthetic studies on the specific inhibitors of vacuolar-type H+-ATPase, bafilomycins, hygrolidines, and concanamycins, are described. Bafilomycins and hygrolidins are 16-membered and concanamycins are 18- membered plecomacrolides, which have very complex molecular structures.