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Nano-formulations for the Management of Epilepsy: Synthetic and Herbal Drug Perspectives
Authors: Shivani, Gurvirender Singh, Smita Narwal, Balram, Bhawna Chopra and Ashwani K. DhingraAvailable online: 24 October 2024More LessIntroduction Epilepsy is a multifaceted neurological disorder impacting many individuals globally. Although the main treatment method is through medicines, many patients do not respond to existing drugs. This has spurred extensive research for new therapeutic targets and drug delivery methods. Inflammation and oxidative stress have been associated with the development and progression of epilepsy. Nanomedicine-bas Read More
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An Overview of Receptor-targeted Nanotechnological Approaches for the Treatment of Metastatic Breast Cancer
Available online: 18 October 2024More LessBreast cancer (BC) is the second most prevalent cancer among women and can originate from the tubes, connective tissue, and lobules of the breast. The primary focus of this review is to highlight the significant advancement in the development of receptor-targeted nanotherapy for the management of metastatic breast cancer. These innovative systems directly target the specific cancer cell receptor to enhance the pre Read More
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Review of Lipid Nanoparticles for Breast Cancer Management: Targeting Strategies and Clinical Perspective
Available online: 17 October 2024More LessChemotherapy, a conventional breast cancer treatment, has limitations due to its non-specific mechanisms and undesirable side effects. Lipid-based nanoparticles (LNPs) have emerged as a versatile and superior platform for targeted breast cancer treatment, offering several distinct advantages over traditional therapies. This class of nanocarriers, which includes solid lipid nanoparticles (SLNs), nanostructured lipid car Read More
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Invasomes: An Artificial Vesicle Nanocarrier to Enhance Transdermal Drug Delivery
Authors: Preeti, Dinesh Puri and Sanjay SinghAvailable online: 16 October 2024More LessThe greatest and most noticeable organ in the body is the skin. The stratum corneum, or top layer of skin, acts as a vital barrier to prevent skin penetration for many drugs. To overcome this barrier, numerous nanocarrier frameworks have been developed, which are important for the functioning of active agents. Vascular systems known as invasomes contain low levels of ethanol as well as terpenes or terpene combin Read More
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Functionalized Carbon Nanotubes: An Advanced Tool with Enhanced Biomedical Attributes
Authors: Tanushka Kataria, Sujit Bose, Shruti Kalia, Vishal Chalotra, Vijay Mishra, Gurleen Kaur and Ankit TyagiAvailable online: 11 October 2024More LessBackground The drug delivery system is revolutionized by nanoparticles, an essential component of nanotechnology, exhibiting an ultra-small size, large surface area to mass ratio, and high reactivity, different from bulk materials having the same composition. Various types of nanoparticles include liposomes, neosomes, micelles, carbon-based, etc. The most useful among them are carbon nanotubes because of their distinct Read More
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Recent Advancement of Novel Drug Delivery Systems for Topical Anaesthesia Formulations
Authors: Sumit Sahu, Vijayalakshmi Ghosh, Parag Jain and AjazuddinAvailable online: 08 October 2024More LessIn recent years, there have been exciting developments in improving how we deliver anaesthesia through the skin. Nanotechnology is a key player, using tiny particles to encapsulate and transport anaesthetic agents, ensuring a controlled and steady release. This helps overcome challenges like inconsistent absorption and short-lasting effects seen with traditional methods. Transdermal patches are gaining attention too; they rele Read More
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Incorporation of Silica Nanoparticles in Dental Stone Type IV: Effects on Setting Time
Available online: 07 October 2024More LessIntroduction This study aimed to examine the setting time of dental stone type IV by adding different percentages (0.5, 1, 2, 5) of silica nanoparticles. Materials and Methods In this in vitro study, silica nanoparticles (silicon dioxide) were added to dental stone type IV at concentrations of 0.5%, 1%, 2%, and 5% by weight. Forty samples were divided into five groups: 0.5%, 1%, 2%, 5%, and a control group. The samples w Read More
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The Nano-Neuro Tempo: An Opinion
Available online: 02 October 2024More LessThe unveiled properties of a wide variety of engineered nano assembly materials, such as nanostructures and quantum dots groups in cell biology and physiology, reveal desired interactivity at a fundamental molecular level. The vast progress in therapeutic strategies developed for nanoscale measurement and manipulation, which have functional nanostructures for sensing and modulating, entails specific interactions with neu Read More
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Formulation and Evaluation of Lungs-Specific Doxorubicin-Loaded Chitosan-PLGA-Alginate Polymeric Nanoparticles
Authors: Shalu Shukla and Vinay PanditAvailable online: 27 September 2024More LessBackground An antibiotic called doxorubicin is produced by the Streptomyces peucetius bacterium, which is a member of the anthracycline drug class and is used in chemotherapy. Usually, doxorubicin is employed to cure solid tumors in children and adult patients. The physical and biological stability of the medicine can be increased by encasing it in nanoparticles, which increases the active pharmaceutical ingredient's bioavai Read More
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Recent Progress in Nanoemulsion Technology for the Management of Hepatic Diseases
Authors: Soniya Sarthi, Harish Bhardwaj and Rajendra Kumar JangdeAvailable online: 25 September 2024More LessLiver diseases pose a significant global health concern, particularly prevalent in developing nations, often induced by chemical exposure and high drug doses. Hepatic toxicity not only affects liver function but also extends to adjacent tissues, leading to diminished overall body function and necessitating effective treatment strategies. Despite modern medical advancements, stimulating liver function, protecting against dama Read More
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