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Cisplatin, also known as cis-(diammine) dichloridoplatinum (II) or CDDP, is frequently used as first-line chemotherapy in head, neck, and lung malignancies. It can be given as a single agent or in conjunction with radiation therapy and/or other anti-cancer chemotherapeutic agents. Now, experiences based on PEGylated liposome-based nano-formulations AroplatinTM, LipoplatinTM, and SPI-077 are undergoing clinical trials. These cisplatin drug delivery systems resolve issues like poor solubility in water, drug resistance, and toxicity by using nanocarrier systems. The above-cited nano-delivery technologies for cisplatin have been extensively described in numerous pieces of literature existing in various databases. Essentially, this evaluation gives a severe focus on newer information, invented news, and up-to-date articles regarding various carrier systems for CDDP and the newer patents of this drug formulation.
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