Cardiovascular Medicine
Are Marital Status and Quality Risk Factors for Cardiovascular Diseases?
Mar 2025
Fast Track Article
Assessment of Left Ventricular Shape Index and Eccentricity Index as Promising Parameters for Detection of Left Ventricular Remodeling in Cardiovascular Events
Mar 2025
Fast Track Article
Journal Title:
Current Cardiology Reviews
Left ventricular remodeling (LVR) refers to the changes in the size shape and function of the left ventricle influenced by mechanical neurohormonal and genetic factors. These changes are directly linked to an increased risk of major adverse cardiac events (MACEs). Various parameters are used to assess cardiac geometry across different imaging modalities with echocardiography being the most commonly employed technique for measuring left ve Read More
Association between Statin use and Abdominal Aortic Calcification in Male, Non-diabetic Elderly
Mar 2025
Fast Track Article
Journal Title:
Current Vascular Pharmacology
Aims Our study was to investigate the association between statin use and the prevalence of abdominal aortic calcification (AAC). Methods The population was enrolled in the 2013-2014 cycle of the National Health and Nutrition Examination Survey (NHANES). The statin use was determined from the questionnaire inquiring the medications taken in the past month. The presence of AAC and severe AAC were assessed based on the AAC score measured by abd Read More
Trends in Readmissions Rates and Mortality after Cardiac Resynchronization Therapy in Patients with Nonischemic Cardiomyopathy
Mar 2025
Fast Track Article
Journal Title:
Current Cardiology Reviews
Introduction Advances in cardiac implanted electronic devices (CIED) have significantly improved outcomes for patients with heart failure. However there is a bereft of recent real-world data on the relative effectiveness of cardiac resynchronization therapy with pacing and defibrillator (CRT-D) and continuous resynchronization therapy with pacing (CRT-P) in patients with nonischemic cardiomyopathy (NICM). We hypothesized that the addition of defibrilla Read More
Unveiling the Complexities: Exploring Mechanisms of Anthracycline-induced Cardiotoxicity
Mar 2025
Article
Source:
Current Cardiology Reviews
21,
E1573403X322928
(2025)
The coexistence of cancer and heart disease both prominent causes of illness and death is further exacerbated by the detrimental impact of chemotherapy. Anthracycline-induced cardiotoxicity is an unfortunate side effect of highly effective therapy in treating different types of cancer; it presents a significant challenge for both clinicians and patients due to the considerable risk of cardiotoxicity. Despite significant progress in understanding these mecha Read More
Diabetic Cardiomyopathy: An Update on Emerging Pathological Mechanisms
Mar 2025
Article
Source:
Current Cardiology Reviews
21,
E1573403X331870
(2025)
Diabetic Cardiomyopathy (DCM) is a notable consequence of diabetes mellitus distinguished by cardiac dysfunction that occurs separately from coronary artery disease or hypertension. A recent study has revealed an intricate interaction of pathogenic processes that contribute to DCM. Important aspects involve the dysregulation of glucose metabolism resulting in heightened oxidative stress and impaired mitochondrial function. In addition persisten Read More
Importance of Zinc Homeostasis for Normal Cardiac Rhythm
Mar 2025
Article
Source:
Current Cardiology Reviews
21,
E1573403X299868
(2025)
Current arrhythmia therapies such as ion channel blockers catheter ablation or implantable cardioverter defibrillators have limitations and side effects and given the proarrhythmic risk associated with conventional ion channel-targeted anti-arrhythmic drug therapies a new approach to arrhythmias may be warranted. Measuring and adjusting the level of specific ions that impact heart rhythm can be a simple and low-complication strategy for preventi Read More
Targeting Wnt Pathways with Small Molecules as New Approach in Cardiovascular Disease
Mar 2025
Article
Source:
Current Cardiology Reviews
21,
E1573403X333038
(2025)
The increasing incidences of morbidity and mortality associated with cardiovascular diseases represent significant difficulties for clinical treatment and have a major impact on patient health. Wnt signaling pathways are highly conserved and are well known for their regulatory roles in embryonic development tissue regeneration and adult tissue homeostasis. Wnt signaling is classified into two distinct pathways: canonical Wnt/β-catenin signaling and non-canoni Read More
Comprehensive Review of Coronary Artery Anatomy Relevant to Cardiac Surgery
Mar 2025
Article
Source:
Current Cardiology Reviews
21,
E1573403X321942
(2025)
In order to perform safe cardiac surgery a knowledge of applied coronary artery anatomy and its variants is essential for cardiac surgeons. In normal individuals the right and the left coronary arteries arise from the corresponding sinuses of Valsalva within the aortic root. From the cardiac surgical perspective the coronary artery is divided into the left main coronary artery its branches (the left anterior descending artery and the circumflex ar Read More
Heart Rate Variability and Heart Failure with Reduced Ejection Fraction: A Systematic Review of Literature
Mar 2025
Article
Source:
Current Cardiology Reviews
21,
E1573403X327105
(2025)
IntroductionAutonomic impairment is a hallmark of heart failure with reduced ejection fraction (HFrEF). While there have been studies on general values for each index of heart rate variability (HRV) analysis in HFrEF a systematic review comprehensively examining representative values in HFrEF is lacking.MethodsWe searched PubMed Embase and Cochrane databases to extract studies reporting representative values of HRV metrics in HFrEF. Read More
Elevated Perspectives: Unraveling Cardiovascular Dynamics in High-Altitude Realms
Mar 2025
Article
Source:
Current Cardiology Reviews
21,
E1573403X308818
(2025)
High-altitude regions pose distinctive challenges for cardiovascular health because of decreased oxygen levels reduced barometric pressure and colder temperatures. Approximately 82 million people live above 2400 meters while over 100 million people visit these heights annually. Individuals ascending rapidly or those with pre-existing cardiovascular conditions are particularly vulnerable to altitude-related illnesses including Acute Mountain Sickne Read More
Atrial Fibrillation-Related Bradycardia and/or Bradycardia-Related Atrial Fibrillation: When and How to Intervene
Mar 2025
Article
Source:
Current Vascular Pharmacology
23,
pp 113
- 135
(2025)
Introduction/ObjectiveAtrial fibrillation (AF) could present with slow ventricular-response; bradycardia could facilitate the emergence of AF. The conviction that one “does not succumb” from bradycardia as an escape rhythm will emerge unless one sustains a fatal injury following syncope is in stark difference with ventricular tachyarrhythmia (VA) which may promptly cause cardiac arrest. However this is not always the case as a life-threatening situation may Read More
Cognitive Behavioral Therapy in Cardiovascular Disease
Mar 2025
Article
Source:
Current Vascular Pharmacology
23,
pp 77
- 97
(2025)
Introduction/ObjectiveThe influence of cognitive behavioral therapy (CBT) and its modalities on various neuropsychiatric conditions is herein explored together with their impact on specific cardiovascular (CV) diseases (CVD).MethodsA comprehensive review of the literature was undertaken via the PubMed Scopus and Google Scholar on the above relevant topics. The focus was on large randomized controlled trials and meta-analyses.ResultsAmong th Read More
Neutrophil Migration is a Crucial Factor in Wound Healing and the Pathogenesis of Diabetic Foot Ulcers: Insights into Pharmacological Interventions
Mar 2025
Article
Source:
Current Vascular Pharmacology
23,
pp 98
- 112
(2025)
Diabetic foot ulcers (DFUs) pose a significant clinical challenge characterized by impaired wound healing chronic inflammation and increased risk of infection. Neutrophils as critical components of the innate immune response play a pivotal role in the initial stages of wound healing particularly during the inflammatory phase. This review explores the intricate relationship between neutrophil migration inflammation and the pathogenesis of DFU and d Read More
The Systemic Immune Inflammation Index as a Novel Predictive Biomarker for Contrast-Induced Acute Kidney Injury Risk Following Percutaneous Coronary Intervention: A Meta-Analysis of Cohort Studies
Mar 2025
Article
Source:
Current Vascular Pharmacology
23,
pp 136
- 145
(2025)
BackgroundContrast-induced Acute Kidney Injury (CI-AKI) frequently occurs as a complication following percutaneous coronary intervention (PCI) making the identification of high-risk patients challenging. While the systemic immune inflammation index (SII) might aid in predicting CI-AKI the current evidence remains insufficient.MethodsWe conducted a systematic literature search using PubMed Web of Science Embase and the Cochrane Library with a Read More
Clinical Predictors of Warfarin Response Among Patients with Atrial Fibrillation: Evidence from the Middle Eastern JoFib Study
Feb 2025
Fast Track Article
Journal Title:
Current Vascular Pharmacology
Objective To describe clinical factors predictive of warfarin response in atrial fibrillation (AF) patients and to evaluate its association with adverse outcomes. Methods Patients in the Middle Eastern JoFib study a prospective multicenter registry of AF patients using warfarin with at least one international normalized ratio (INR) reading were enrolled. We used the most recent INR as a measure of warfarin control. Results Out of the total 2020 patients 544 (26.9 Read More
Comparison of Clinical Outcomes between Newly Diagnosed and Pre-Existing Diabetes Mellitus Patients after Acute Coronary Syndrome
Feb 2025
Fast Track Article
Journal Title:
Current Vascular Pharmacology
Aims This study aimed to evaluate clinical outcomes including recurrent acute coronary syndrome (ACS) and mortality in ACS patients with varying HbA1c levels addressing the controversy over optimal targets in those with newly diagnosed and pre-existing diabetes mellitus (DM). Methods From January 2005 to December 2019 a total of 33990 patients were identified with ACS in the Chang Gung Research Database based on their medical history. After excl Read More
Evaluation of Cardiovascular and Hepatic Changes in Myocardial Infarction Patients Post-Covid-19 Vaccination
Feb 2025
Fast Track Article
Journal Title:
Current Vascular Pharmacology
Introduction The global COVID-19 vaccination campaign has significantly reduced severe illness and mortality; however emerging evidence raises concerns regarding its potential cardiovascular effects particularly myocardial infarction (MI). Method This study investigates the relationship between COVID-19 vaccination and MI incidence among first-time MI patients in Saudi Arabia. Post-COVID-19 vaccination within six months post-vaccination accounte Read More
Tumor-Associated Pericytes: Tumorigenicity and Targeting for Cancer Therapy
Feb 2025
Fast Track Article
Journal Title:
Current Vascular Pharmacology
Pericytes also known as mural cells are cells embedded between endothelial cells and the basement membrane of capillaries where they orchestrate the morphological and functional homeostasis of blood vessels. Within the tumor microenvironment pericytes interact closely with various cellular components including tumor cells stromal cells and immune cells. Through these dynamic interactions pericytes are activated and subsequently transform into Read More
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