The excessive exploitation of antibiotics for the treatment of bacterial illnesses has resulted in the emergence of several strains that are resistant to different drugs. Due to the widespread occurrence of antibiotic resistance and the emergence of bacterial strains that are resistant to various drugs significant efforts are being made to identify appropriate alternative medicines to combat harmful microorganisms. Given the observed link between biofilm formati Read More

BackgroundThe worldwide increase of antimicrobial resistance in ESKAPE pathogens which includes Enterococcus faecium Staphylococcus aureus Klebsiella pneumoniae Acinetobacter baumannii Pseudomonas aeruginosa and Enterobacter sp. constitutes a substantial public health hazard constraining treatment alternatives and elevating morbidity and mortality rates. As traditional antibiotics diminish in efficacy phytochemicals are capturing interest due to Read More

Cognition encompasses the interdisciplinary scientific study of the brain and its processes including intelligence and behavior in living beings. While humans are typically born with the capacity for cognitive function certain conditions such as infection and oxidative stress can lead to impaired cognition. Herbal drugs and phytochemicals are utilized to enhance cognitive functions and alleviate symptoms associated with impaired cognition. Despite ongoing Read More

In the field of pharmaceutical research expert tool has become a game-changing tool that is altering many aspects of drug discovery and development. Understanding the physicochemical characteristics of drug candidates is essential for developing formulation methods and this is where preformulation studies come into play. The incorporation of expert tools in preformulation research is thoroughly examined in this review which also highlights the Read More

IntroductionChronic stress serves as a fundamental factor contributing to various health conditions including atherosclerosis hypertension and cardiac dysfunction. Previous findings from our laboratory have revealed a clear link between chronic stress and increased occurrence of heart dysfunction atherosclerosis immune imbalance and psoriasis. However the haematological and metabolic pathways involved remain unexplored. Therefore ou Read More

HIV and Tuberculosis (TB) are the leading global causes of death among patients with infectious diseases. They contribute significantly to morbidity around the world because of their impact on shared immune defense mechanisms. Tuberculosis is an infection that exploits the vulnerability of compromised immune systems. Opportunistic infections are illnesses that are more frequent or severe in individuals with compromised immune systems. HIV w Read More

Due to the biological importance of amino acids the development of optical probes for these compounds has become a popular research topic in recent years. The amino acid fluorescence or colorimetric sensors are organized according to the reactions the amino acids go through and the related structural classification. Works on reaction-based chemosensors are categorized as either imine formation Michael addition thiazinane or thiazolidine format Read More

The oxygen reduction reaction (ORR) is vital to numerous energy conversion technologies such as fuel cells and metal-air batteries. Moreover to enhance the overall efficacy and durability of these devices it is crucial to develop catalysts that are both effective and economical. Among the many explored catalyst materials cobalt chalcogenides have attracted considerable interest due to their unique properties and exceptional ORR performance. This review Read More

BackgroundCritical monitoring of moisture content in annulus gas is required due to its detrimental effect on the pressure tube leading to surface corrosion and finally the rupture of the pressure tube.Methods and ResultsThe present work describes a simple and reliable thermo-analytical method for the quantitative determination of moisture in CO2 gas cylinders using anhydrous barium chloride as the novel adsorbent material and simultaneous. T Read More

The COVID-19 emergency built pressure on US regulatory bodies to unlock the optional and short pathway of approval for urgently required pharmaceuticals to accomplish population demand for medicinal products within the shortest possible time to limit the suffering and deaths associated with insufficiency of medicinal products in need. During the pandemic many medicinal products got emergency use authorization (EUA) according to the EUA guideline Read More