Recent Advances in Inflammation & Allergy Drug Discovery - Volume 18, Issue 2, 2024

Flos Magnoliae is one of the important medicinal plants in different traditional medicine, including Chinese herbal medicine. Lignans and neolignans, including tetrahydrofurofuran, tetrahydrofuran, and aryltetralin, are present in the Flos Magnoliae species. A wide range of pharmacological activity of Flos Magnoliae has been reported in medicine. Fargesin has been isolated from Magnolia fargesii and it is a lignan-class phytochemic Read More

A complicated biological reaction of vascular tissues to damaging stimuli like infections, harmed cells, or irritants is called inflammation. Symptoms include redness, inflamed joints, stiffness, discomfort in the joints, and loss of joint function. NSAIDs are frequently used to treat inflammation. Sadly, these drugs raise the possibility of blood clots, which can result in heart attacks and strokes. Consequently, there is ongoing resea Read More

Background: Chronic rhinosinusitis is known as a common problem with inflammatory and allergic causes. Several factors are associated with developing chronic rhinosinusitis, including immunoglobulin E (IgE) production and vitamin D deficiency. Objective: In this study, we investigated the role of IgE and Vitamin D deficiency and differences between patients with chronic, allergic sinusitis and controls. Methods: A total of 90 Read More

Background The annual incidence of peptic ulcer disease is estimated to be four million cases worldwide, with an average lifetime risk of 7.5% in individuals of all ages. Polymer nanocomposites have novel prospects in the field of modern medicine. Objective The present research endeavors to assess the therapeutic efficacy of nanoparticles composed of silver/chitosan, silver/saponin, and chitosan/saponin against gastric ulcers i Read More

Background Cutaneous leishmaniasis (CL) is a parasitic disease with a significant burden in the Old World countries. Objective In the current study, some of the primary biochemical properties and IFN-γ inducing epitopes with specific binding capacity to human and mouse MHC alleles were predicted for Leishmania major gp46 antigenic protein. Methods Several online servers were used to predict physico-chemical traits, all Read More

Background Diseases are medical situations that are allied with specific signs and symptoms. A disease may be instigated by internal dysfunction or external factors like pathogens. Cerebrovascular disease can progress from diverse causes, comprising thrombosis, atherosclerosis, cerebral venous thrombosis, or embolic arterial blood clot. Objective In this paper, authors have proposed a robust framework for the detection Read More

Objective: At present, no proven effective treatment is available for Lung Ischemia-reperfusion Injury (LIRI). Natural compounds offer promising prospects for developing new drugs to address various diseases. This study sought to explore the potential of Rebaudioside B (Reb B) as a treatment compound for LIRI, both in vivo and in vitro. Methods: This study involved utilizing the human pulmonary alveolar cell line A54 Read More