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- Volume 28, Issue 7, 2022
Current Pharmaceutical Design - Volume 28, Issue 7, 2022
Volume 28, Issue 7, 2022
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Venous Thromboembolism in Patients with Heart Failure
Heart failure (HF) and venous thromboembolism (VTE) are common clinical entities, closely interrelated, sharing multiple pathophysiological mechanisms. Their co-incidence is associated with further worsening of the prognosis of one another. Despite their frequent co-existence, important clinical questions still remain unanswered. The risk of VTE especially in chronic HF patients appears to vary widely in clinical st Read More
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Surgical Treatment of Pulmonary Embolism and Chronic Thromboembolic Pulmonary Hypertension
Venous thromboembolism clinically presents as deep venous thrombosis or acute pulmonary embolism and is globally recognized as the third most frequent acute cardiovascular syndrome after myocardial infarction and stroke. Although pulmonary embolism does not typically cause severe pulmonary hypertension in the acute setting, thrombus organization and fibrosis can lead to stenosis or obliteration of pulmonary arteri Read More
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Pulmonary Embolism Response Team (PERT) - A New Paradigm for the Treatment of Pulmonary Embolism
Authors: Jonathan Koslowsky, Amit Kakkar, Robert T. Faillace and Seth I. SokolPulmonary embolism (PE) is the third leading cause of cardiovascular mortality. Patients with PE can present with a wide array of symptoms, ranging from mild to life threatening. The mainstay of PE treatment is anticoagulation; however, many advanced options are available for more severe patients, including catheter- directed interventions, surgical treatments, and hemodynamic support. Although different risk score Read More
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Management of Post-thrombotic Syndrome: A Comprehensive Review
Background: Post-thrombotic syndrome (PTS) is the most common long-term complication of acute deep venous thrombosis (DVT). The cumulative incidence of PTS in the first two years after the first acute DVT diagnosis approximates 25%. Objective: This study aims to summarize the most recent updates and provide a comprehensive review of the current management of PTS. Methods: We searched MEDLINE/PMC/NCBI Bo Read More
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Prospective for Diagnosis and Treatment of Diabetic Retinopathy
Authors: Faiza I. Himasa, Manmohan Singhal, Abhijeet Ojha and Bhavna KumarDiabetic retinopathy is a posterior eye disorder in which damage occurs to the light sensitive retina due to diabetes mellitus. This disorder specifically affects people aged between 18-64 with type II diabetes. This disease progresses through different pathophysiological pathways, which include oxidative stress, inflammation, stimulation of the growth factor in the eye’s vasculature, isoforms of protein kinase C, and also th Read More
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Bacterial Nanocellulose based Wound Dressings: Current and Future Prospects
Authors: Hitesh Chopra, Shweta Gandhi, Rupesh K. Gautam and Mohammad Amjad KamalAlthough there are many treatment options available for wound and burns dressings, improvements in technology are still required. Bacterial cellulose is a polymer derived from the microbiological world and has shown some promising properties that recommend it as a wound healing therapeutic. Moreover, bacterial cellulose can be nanosized to form Bacterial Nanocellulose (BNC), enhancing its properties. Most impor Read More
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The Regulatory Role of Both MBNL1 and MBNL1-AS1 in Several Common Cancers
Authors: Qi Zhang, Yinxin Wu, Jinlan Chen, Fangshun Tan, Jie Mou, Zhuoying Du, Yuxuan Cai, Bei Wang and Chengfu YuanBackground: Muscle blind-like-proteins (MBNL) are a class of tissue-specific RNA metabolism regulators that control pre-messenger RNA-splicing. Inactivation of MBNL can lead to myotonic dystrophy in adults. MBNL is mainly expressed in skeletal muscle, neuron tissue, thymus, liver, and kidney and plays an important role in the ultimate differentiation of muscle cells and neurons. MBNL1 is a member of the MBNL protein f Read More
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Testosterone Supplementation on Sarcopenia Components in Chronic Patients: A Systematic Review and Meta-Analysis
Authors: Camila Correa, Patrícia Bieger, Ingrid S. Perry and Gabriela C. SouzaBackground: Sarcopenia is a progressive and generalized skeletal muscle disorder with unfavorable muscle changes throughout life, which can be associated with chronic disease. Testosterone supplementation is emerging as a possible therapy; however, it is still necessary to explore its effectiveness. Objectives: This systematic review and meta-analysis aimed to evaluate and summarize the evidence related to the effect Read More
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Volumes & issues
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Volume 31 (2025)
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Volume 30 (2024)
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Volume 29 (2023)
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Volume 28 (2022)
- Issue 46
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- Issue 1
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Volume 27 (2021)
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Volume 26 (2020)
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Volume 25 (2019)
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Volume 24 (2018)
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Volume 23 (2017)
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Volume 22 (2016)
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Volume 21 (2015)
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Volume 20 (2014)
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Volume 19 (2013)
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Volume 18 (2012)
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Volume 17 (2011)
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Volume 16 (2010)
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Volume 15 (2009)
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Volume 14 (2008)
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Volume 13 (2007)
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Volume 12 (2006)
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Volume 11 (2005)
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Volume 10 (2004)
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Volume 9 (2003)
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Volume 8 (2002)
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Volume 7 (2001)
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Volume 6 (2000)
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