Current Pharmaceutical Design - Volume 28, Issue 42, 2022

Background: Pulmonary microbial infection is mainly caused by microbes like atypical bacteria, viruses, and fungi, on both the upper and lower respiratory tracts. One of the demands of the present is the use of nanotechnology-based treatments to fight various lung infections. Aim: The main aim of the study is to explore all pulmonary infectious diseases and to compare the advanced and novel treatment approaches wit Read More

Background: Imbalances in dopamine levels result in neurological and psychological disorders such as elevated dopamine in Parkinson’s disease. Objective: Despite a considerable number of advertisements claiming Aloe-vera’s effectiveness in PD treatment, it has hidden long-term disadvantages for healthy people and PD patients. Methods: In the present investigation, the impacts of Aloe-vera on dopaminergic cells Read More

Background: Although the majority of members belonging to the small GTPase Ras superfamily have been studied in several malignancies, the function of RBJ has remained unclear, particularly in non-small cell lung cancer (NSCLC). Objective: The research aims to determine the function of RBJ in NSCLC. Methods: The levels of RBJ protein in tumor tissue and para-carcinoma normal tissue were ascertained via immunohistoch Read More

Background: The mechanism of Heat Shock Protein 90 (HSP90) in Ulcerative Colitis (UC) has been studied, and mitogenic-activated protein kinases (MAPK) also contribute to the pathogenesis of UC. However, the effect of the HSP90/MAPK pathway in UC is still unclear. Therefore, the mainstay of this research is to explore the mechanism of action of this pathway in UC. Compound sophorae decoction (CSD), as a Chinese herbal de Read More