Current Pharmaceutical Design - Volume 28, Issue 13, 2022

Cancer is a disease characterized by uncontrolled cell proliferation and the spread of cells to other tissues and remains one of the worldwide problems waiting to be solved. There are various treatment strategies for cancer, such as chemotherapy, surgery, radiotherapy, and immunotherapy, although it varies according to its type and stage. Many chemotherapeutic agents have limited clinical use due to lack Read More

Marine sources have attracted much interest as an emerging source of biomaterials in drug delivery applications. Amongst all other marine biopolymers, polysaccharides have been the most investigated class of biomaterials. The low cytotoxic behavior, combined with the newly explored health benefits of marine polysaccharides, has made it one of the prime research areas in the pharmaceutical and biomedical fields. Thi Read More

Alginate-based biomaterials have been extensively studied for bone tissue engineering. Scaffolds, microspheres, and hydrogels can be developed using alginate, which is biocompatible, biodegradable, and able to deliver growth factors and drugs. Alginate microspheres can be produced using crosslinking, microfluidic, three-dimensional printing, extrusion, and emulsion methods. The sizes of the alginate microspheres range fro Read More

Introduction: Psoriasis is an incurable, non-contagious inflammatory autoimmune skin disease characterised by abnormal skin redness and flaky patches on the body surface. It is caused by negative signals produced by the immune system, leading to excessive growth and differentiation of keratinocytes and other inflammatory reactions on the skin. The topical route is primarily preferred in treating skin disorders due to the Read More

Background: Neuronal cell apoptosis is associated with radiation exposure. It is urgent to study the radiation protection of hippocampal neurons. Objective: The purpose of this study was to investigate the protective effect of anthocyanins on radiation and its potential mechanism. Materials and Methods: The irradiation was carried out at room temperature with 4-Gy dose. Anthocyanins were intraperitoneally administered to Read More