Current Pharmaceutical Analysis - Volume 20, Issue 6, 2024

Selective Serotonin Reuptake Inhibitors (SSRIs) are a key development in psychological pharmacology and treatment. It has been demonstrated that serotonin (5-HT) has a pharmacological role in a variety of anxiety- and mood-related conditions. Fluvoxamine, citalopram, escitalopram, paroxetine, sertraline, and fluoxetine are the six primary SSRIs now available in the United States for the treatment of depression and a Read More

Precise measurement of drug concentration in pharmaceutical research is critical, especially for anti-viral drugs like boceprevir, elvitegravir, indinavir, and saquinavir that combat viral infections. It is well-known that analytical techniques play an imperative role in identifying and characterizing active pharmaceutical ingredients in biological samples and drug formulations. Moreover, precise drug assessment direct Read More

ObjectiveThe objective of the research was the development and validation of a simple, sensitive, accurate, robust, and precise UV-spectroscopic method for the quantitative determination of chlorogenic acid loaded in solid-lipid nanoparticles as per the guidelines of the International Conference on Harmonization.MethodsThe solid-lipid nanoparticles of chlorogenic acid were prepared using the hot melt emulsification Read More

BackgroundIn the current study, a simple and cost-effective stability-indicating RP-HPLC method was developed and validated to estimate the mesalamine from both bulk and pharmaceutical dosage forms.MethodsAn isocratic HPLC method using a reverse phase HiQSilC18 column (250 x 4.6 mm, 5µm) and a mobile phase methanol: ammonium acetate buffer (90:10 v/v) were employed as the mobile phase with a flow rate Read More

Background Carbamide peroxide (CP) is a hydrogen peroxide derivative bonded with urea. It is a solid substitute for liquid hydrogen peroxide in the chemical, cosmetics, and pharmaceutical industries, mainly as a disinfectant and bleaching application. However, it has an unstable nature, and there are scant studies on CP thermal analysis. Objective This study focuses on CP thermal analysis and degradation behavior. Methods Read More