Current Organic Chemistry - Volume 29, Issue 9, 2025

Novel bispidine skeleton has been extensively designed as bifunctional chelators (BFCs) for their special stereochemical structure and variable dentate numbers. Bispidine-based ligands (BBLs) as BFCs generally integrate the benefits of conventional acyclic and macrocyclic BFCs, demonstrating exceptional radiolabeling kinetics, thermodynamic stability and kinetic inertness for their metal complexes. The accessibl Read More

Under the broad domain of multimetallic catalysis, the utilisation of two transition metals (either homometallic or heterometallic) as catalysts in a cooperative way to enhance reactivity and promote higher stereoselectivity and versatility has witnessed remarkable advancements in organic synthesis in the last two decades. This review attempts to provide an account of the development in the recent past to its progress now i Read More

Heterocyclic compounds with a pyridine structure are important in organic chemistry because they are found in many pharmaceuticals, agrochemicals, and natural substances. Traditional methods to create pyridines use harsh conditions and toxic chemicals, which can be harmful to the environment and human health. Recently, there has been interest in using ionic liquids (ILs) as a sustainable alternative for these re Read More

Indoles are critical in natural amalgamation for their flexible jobs in drugs, regular items, and material science, exhibiting huge pharmacological and compound reactivity. Due to their versatility and high reactivity, nitroalkenes are essential electrophilic partners in organic synthesis. While indoles and nitroalkenes are used in both Michael addition and Friedel-Crafts alkylation for producing carbon-carbon bonds, the catalyst t Read More

Imidazopyridine holds significance as a crucial fused bicyclic heterocycle within the realm of medicinal chemistry, being acknowledged as a “privileged scaffold” owing to its extensive utility. Numerous methodologies for the synthesis of imidazo[1,2-a]pyridines have been documented, with a considerable focus on strategies aimed at functionalizing these compounds. This study aimed to explore the potential of novel imi Read More