Current Organic Chemistry - Volume 29, Issue 10, 2025

This review article explores the direct oxidation of primary alcohols into carboxylic acids, highlighting its importance in organic synthesis for producing valuable chemicals in a sustainable and efficient manner. Carboxylic acids are widely employed in a wide range of applications, encompassing food preservatives, insecticides, dye intermediates, coatings, plasticizers, spices, flavors, scents, and a variety of industri Read More

Coumarins are a vital class of compounds recognized for their significant therapeutic potential, both in their natural forms and as synthetic derivatives. Characterized by a benzene ring fused to an α-pyranose ring, coumarins have garnered considerable attention from the scientific community due to their diverse pharmacological activities. This review article highlights the importance of coumarin hybrids, showcasin Read More

A series of sixteen new 4-(substituted phenyl)-6-(substituted phenylamino)-3,4-dihydropyrimidine-2(1H)-one/thione derivatives have been synthesized in two-step reaction. In the first step, chalcones (I1-I6) were obtained, and in the second step, these chalcones were reacted with urea and thiourea in the presence of potassium hydroxide to obtain the corresponding pyrimidinones and thiopyrimidinones. The progress of Read More

This study aimed to synthesize a total of seven halogenated amidostilbenes 3a-3f using the Heck cross-coupling method. The synthesized stilbenes underwent further reactions with Lewis acids, such as FeCl3 and SnCl4, resulting in imines 4 and indolines 5, respectively. The structure of all synthesized compounds was elucidated using FTIR, 1D- and 2D-NMR, XRD, and HRMS analysis. Furthermore, the mechanistic details und Read More