Current Cancer Therapy Reviews - Volume 21, Issue 2, 2025

Cancer therapy has evolved beyond targeting malignant cells alone, recognizing the pivotal role of the tumor microenvironment (TME) in disease progression. Enzyme micellar systems, a subset of nanomedicine, offer a cutting-edge approach by exploiting the intricate interplay between therapeutic delivery and the TME. Engineered to respond to enzymatic cues, these systems enable targeted drug delivery, controlled rel Read More

This article highlights the therapeutic use of electrospun biopolymers in cancer treatment. An overview of cancer and electrospun is presented at the beginning. The reasons for electrospinning, the elements that influence electrospinning, and the most recent breakthroughs in the utilization of electrospun nanofibers in cancer research are then explored. The insertion of drugs, managing emission kinetics, alignment and proper Read More

BackgroundAtractylodes lancea Thunb. (Asteraceae) is a commonly used medicinal plant for gastric and appetite-associated complications in traditional Chinese medicine. The rhizome of Atractylodes lancea has been widely used for the treatment of human complications. Atractylodin has anti-angiogenic, anti-cancer, anti-inflammatory, anti-microbial, anti-pyretic and anti-hypertensive potential in medicine. Nano-formulatio Read More

Chemotherapy is a multimodal strategy that entails very complicated regimens to treat cancer. Despite the better effectiveness and increased longevity afforded by chemotherapy, its side effects and long-term sequelae continue to be significant causes of worry for both physicians and patients. The patients often experience nausea, vomiting, cardiac toxicity, lung toxicity, hepatotoxicity, nephrotoxicity, etc., as adverse d Read More

Non-small cell lung cancer (NSCLC) is a ubiquitous form of lung cancer. Most patients already have metastasis at the time of diagnosis. Chemotherapy and radiotherapy are widely used to treat the early stages of NSCLC, but cancer relapses are common, and the mortality rate is also high. Hence, there is a definite need for newer and advanced therapies to control the recurrence and metastasis of NSCLC. Many cl Read More

Colorectal cancer (CRC) ranks as the third most prevalent cancer type and the second leading cause of cancer-related deaths globally. The mortality rate from colon cancer has seen a significant increase, correlating with the widespread adoption of Western dietary habits and lifestyles. Medicinal plants, notably those containing functional phytochemicals like polysaccharides, exhibit anti-tumor and anti-apoptotic properti Read More

BackgroundFlavonoids, one of the major bioactive constituents of herbal drugs, have been scientifically reported to possess diverse therapeutic potentials such as anticancer, immunomodulatory, neuroprotective, cardioprotective, antioxidant, etc. This manuscript enlightens the anticancer potential of traditional herbal flavonoids in gynecological cancer i.e., is one of the major life-threats in women.ObjectiveThis manuscript i Read More

IntroductionSkin cancer is the fifth most common cancer and is a serious concern to public health and the economy. Although, various treatment strategies are available but have several undesirable side effects. To combat these drawbacks, phytoconstituents or herbs can be the best choice. Uraria picta (prishniparni) is a potential herb used in various herbal formulations, important of which is Dasmularishta.MethodsThus, the Read More

IntroductionBordeline Brenner tumors of the ovary are rare tumors accounting for 2% of all ovarian tumors and are characterized by the presence of papillary structures covered with transitional epithelium without or minimal stromal invasion.Case PresentationIn the present case report a 60-year-old postmenopausal woman presented with complaints of lower abdominal pain and a right ovarian mass of 4x5cm, which was dia Read More