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- Volume 23, Issue 2, 2025
Anti-Infective Agents - Volume 23, Issue 2, 2025
Volume 23, Issue 2, 2025
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Insight into the Potential Antiviral Properties of the Genus Clerodendrum: Bioactive compounds with Mechanism of Action
Authors: Shubham Bhattacharyya, Mayukh Hore and Subhrajyoti RoyBackgroundAntiviral compounds from plant origin have been the focus of researchers throughout the world for a long time as the potential alternative to classical antiviral therapies. The search for antiviral phytochemicals comes into the limelight amidst the recent COVID-19 pandemic. This tremendous surge in the hunt for effective and alternative treatment from the plant source is mainly due to the toxicity and inadeq Read More
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Herbal Antibiotics: A Review of Traditional Medicinal Plants with Antibacterial Properties and Their Potential for Future Treatment
BackgroundThe active ingredient in medicinal herbs has a considerable therapeutic impact. Historically, medicinal plants have been critical in helping people recover from unfavorable microbial infection-related illnesses. Therefore, we can use these plants as raw materials to make antibiotics.ObjectivesTo summarize, several traditional herbs have antibacterial properties, and their use as a therapy option offers a suc Read More
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From Plants to Pills: Malaria Treatment Advancements in India
Authors: Navpreet Kaur, Jhilli Basu, Shanu Raina, Sana Sood, Diksha Chauhan and Priya JaswalSince 2019, the world's primary focus has been shifted towards the new virus, i.e., coronavirus. So, on a priority basis, the global interest shifts increasingly to fighting a battle against this pandemic, but what about other infectious diseases like malaria? In regions with limited resources (Sub-Saharan Africa, South Asia, and Southeast Asia), malaria remains a significant health threat, transmitted by mosquitoes and caused by t Read More
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Chemical Composition and Antiparasitic Effects of Prangos ferulacea (L.) Lindl., Essential Oil against Echinococcus granulosus Protoscoleces
IntroductionHydatidosis is an infectious disease that occurs in the larval stage of Echinococcus granulosus. Benzimidazoles are the only official and approved drugs for treatment, but their effectiveness varies among patients. Therefore, safe discoveries are needed for new and safe herbal medicines and supplements to improve the treatment of this disease. The current research was carried out to investigate the chemical Read More
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In silico Screening of Plectranthus amboinicus and Hyptis suaveolens Phytochemicals: Novel Repellents Targeting Odorant Binding Proteins of Aedes aegypti and Aedes albopictus
Background and AimMosquitoes significantly threaten public health, transmitting dangerous diseases to humans and animals. Conventional insecticide spraying, while common, has limitations in effectively controlling vector-borne diseases. Many chemical pesticides harm humans and animals, and some persist in the environment and cause toxic effects. Recently, there has been renewed interest in plant-based product Read More
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Evaluation of the Antioxidant and Antimicrobial Properties of Hydrosol Extract and Essential oil Derived from the Aerial Parts of Salvia argentea
BackgroundThe increasing use of synthetic antimicrobials and antioxidants is a concern for human health.AimsThe main objective of this study was to examine the chemical composition of the Essential oil extracted from Salvia argentea and its hydrosol extract while evaluating their antioxidant and antimicrobial effects in vitro.Materials and MethodsThe Essential oil was obtained by hydrodistillation, while the hydrosol extract was Read More
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Synthesis, Characterization, Molecular Docking, and Molecular Dynamics Studies of Schiff Bases of 2-Phenoxy-1-Phenyl-Ethanone as Antibacterial Agents
Authors: Akarsh Agrawal, Nitin Sati, Arvind Kumar and Sushil KumarBackgroundThe development of antimicrobial resistance and reduced discovery and commercialization of newer antibiotics point to the need for the discovery of novel antibacterial agents. Schiff bases are reported to possess a broad range of pharmacological activities, which also include antibacterial activity. With this background, novel Schiff bases were synthesized.AimThe present study aimed to synthesize novel Schiff b Read More
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An Overview of the Pharmacological and Phytochemical Characteristics of Betula utilis
BackgroundBetula utilis, commonly known as the Himalayan Birch or Bhojpatra, has been used for centuries in Traditional Chinese Medicine (TCM) for its diverse pharmacological and phytochemical properties. This overview delves into the rich history and therapeutic applications of Betula utilis from a TCM perspective. It discusses its role in promoting health and addressing various ailments, drawing on the wisdom of traditional Read More
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In-silico Screening of Natural Compound Library against COVID-19 Main Protease
AimsTo perform in-silico screening of the natural phytoconstituents against COVID-19 main protease.BackgroundCOVID-19 is an atypical virus that is universal around the globe. WHO (World Health Organization) has also affirmed the emergency public health concerns regarding COVID-19. As COVID-19 spreads globally within a shorter duration, there is a great demand for effective therapy with minimal side effects.ObjectiveTo Read More
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The Frequency of Aminoglycoside and Vancomycin-resistant Genes in Enterococci Isolated from Chicken Meat in Qom City, Iran
Authors: Somayeh Dehghani Sanij, Pegah Shakib and Abbas MorovvatiBackground and PurposeConsidering the emergence of antibiotic resistance in enterococci and the possibility of transmission of resistant strains to humans, their spread in natural reservoirs is of particular importance. The food chain is known as a source of enterococci that is resistant to antimicrobial agents, and these bacteria are present in foods of animal origin, such as meat and milk. Hence, the purpose of this study Read More
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