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Volume 23, Issue 2
  • ISSN: 2211-3525
  • E-ISSN: 2211-3533

Abstract

Background

The increasing use of synthetic antimicrobials and antioxidants is a concern for human health.

Aims

The main objective of this study was to examine the chemical composition of the extracted from and its hydrosol extract while evaluating their antioxidant and antimicrobial effects .

Materials and Methods

The was obtained by hydrodistillation, while the hydrosol extract was obtained by the liquid-liquid extraction method. The volatile compounds of the and hydrosol extract were analysed by gas chromatography (GC/FID) and gas chromatography coupled with mass spectrometry (GC/MS). Antioxidant activities were evaluated using two methods: free radical scavenging activity (DPPH) and iron reduction antioxidant power (FRAP), with BHT used as a positive control. The antimicrobial activity of the and hydrosol extract was evaluated using the agar disc diffusion method.

Results

According to the GC/FID and GC/MS analysis, the of consisted mainly of germacrene D-4-ol (26.3%), epi-α-muurolol (19.2%), and epi-α-cadinol (10.2%). In contrast, the hydrosol extract consisted of oxygenated compounds, including (E)-phytol (23.5%), 14-hydroxy-δ-cadine (17.5%), caryophyllene oxide (11.5%), piperitone (13.5%), and piperitone oxide (11.5%). The and hydrosol extract showed positive antioxidant activity with both tests. It should be noted that the hydrosol extract showed the best performance, with an IC of 8.3 g/L with the DPPH and an IC of 12.3 g/L with the FRAP test compared to the BHT. The revealed antimicrobial activity with strong inhibition against , , , and compared to Gentamicin.

Conclusion

The results showed that and hydrosol extract have promising antimicrobial and antioxidant properties. These findings provide encouraging prospects for their potential use in the pharmaceutical or cosmetic sectors.

© 2025 Bentham Science Publishers
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2024-07-03
2025-01-16

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Evaluation of the Antioxidant and Antimicrobial Properties of Hydrosol Extract and Essential oil Derived from the Aerial Parts of Salvia argentea
Anti Infect. Agents 23, e030724231513 (2025); https://doi.org/10.2174/0122113525303193240606062041
/content/journals/aia/10.2174/0122113525303193240606062041
/content/journals/aia/10.2174/0122113525303193240606062041
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  • Article Type:     Research Article
Keyword(s): agar dicc diffusion method; antimicrobial activities; antioxidant activities; Essential oil; gas chromatography; Hydrosol extract

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