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Recent Advances in Nanoformulations of Citrus Bioactives & Potential Health Benefits
Authors: Minakshi Verma and Alok Kumar DasAvailable online: 07 January 2025More LessCitrus fruits are widely recognized not only for their refreshing taste but also for their rich content of bioactive compounds, including flavonoids, carotenoids, and essential oils. The molecular mechanisms through which citrus-derived compounds exert their effects highlight their antioxidant, anti-inflammatory, anticancer, and cardioprotective properties. Flavonoids, such as hesperidin and naringin, exhibit potent antioxidant a Read More
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Review of Advancements and Future Directions in the Fabrication of Microchannel Heat Sinks for Electronic Cooling
Authors: Sasmita Bal, Ankit D. Oza and Manoj KumarAvailable online: 30 December 2024More LessWith the increasing demand for enhanced thermal performance and energy efficiency, microchannel heat sinks (MCHSs) have garnered significant attention as an effective method for dissipating the heat flux from thermal systems. Microchannel heat sinks have widespread applications in electronic devices, offering superior heat removal rates and ensuring optimal performance and durability. The fabrication of microchann Read More
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Enhancing Acyclovir Permeability Using SLS Crosslinked β-Cyclodextrin Nanoparticles
Authors: Priyanka Gauniya, Radheshyam, Sukirti Dobriyal, Mukesh Pandey, Ajay Semalty and Mona SemaltyAvailable online: 20 December 2024More LessIntroduction/Objective Acyclovir, a BCS class III drug (that has high solubility and low permeability) is an antiviral drug used for the treatment of herpes simplex and varicose zoster. To enhance acyclovir's permeability across the intestinal membrane and to improve its bioavailability the β-cyclodextrin (β-CD) nanoparticles of acyclovir were prepared with sodium lauryl sulfate (SLS) as a crosslinking agent. Methods A phase s Read More
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Black Carbon Nanoparticles in Atmospheric Aerosols: Update on Functional Groups
Available online: 20 December 2024More LessAerosols are fine particles in the atmosphere produced by nature or man-made like fog, forest exudates, industrial emissions, biomass burning, and dust. Aerosols can change the earth's climate, and the formation of clouds, and may reduce the rain as they circulate in the atmosphere. Black carbon, also called soot is the dominant form of particles in the atmosphere which absorb light. They are fine particles and are smaller t Read More
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Helicobacter Pylori-induced Duodenal Ulcer: An Experimental Animal Model for Scientific Research
Authors: Ayushi Gupta and Trilochan SatapathyAvailable online: 12 December 2024More LessObjectives The objective of this review is to study the duodenal ulcer caused by helicobacter pylori using experimental animal models. Methods Animal models play an important role in the screening of new drugs and compounds to establish their safety and effectiveness. Peptic ulcer (PU) is a heterogeneous multifactorial disorder of known and unknown etiologies and may be caused by the imbalance between the mucosal d Read More
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Novel Design of EXOR Gate and its Application for Circuits using QCA Nanotechnology
Authors: Vijay Kumar Sharma, Gulista Khan, Neeraj Kaushik and Sudakar Singh ChauhanAvailable online: 12 December 2024More LessBackground QCA nanotechnology is an emerging technology in the current scenario to develop the digital circuits for area-efficient, energy-efficient, low-power, and high-speed applications. The EXOR gate is broadly used in many digital applications. Therefore, an EXOR gate needs to be designed in an emerging technology to tackle the issues of the nanoscale regime of conventional metal oxide semiconductor (MOS) tec Read More
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Curcumin Nanoparticles: Exploring Types and Their Impact on Biopharmaceutical Performance
Authors: Priyanka Gauniya, Radheshyam, Ajay Semalty and Mona SemaltyAvailable online: 10 December 2024More LessTurmeric (Curcuma longa) contains a polyphenol called curcumin, which has a variety of medicinal uses, including anti-inflammatory, antioxidant, and anticancer effects. However, due to its rapid disintegration, low solubility, and poor absorption, its clinical application is restricted. To overcome these challenges, researchers are exploring the use of various kind of curcumin nanoparticles, which enhance its solubility, stability, and Read More
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Design of Cascode Current Mirror Using CMOS Technology for Low Power Application
Authors: Kudakwashe Muzira, Sweta Chander and Sanjeet Kumar SinhaAvailable online: 07 November 2024More LessBackground Many applications, including biological applications, require a very high output impedance current mirror because they run at very low voltages. The circuit known as the current mirror applies the idea that two identical MOS transistors with the same gate-source voltage will have equal channel currents flowing through them. Objective The objective of this study is to optimize the design to minimize power consump Read More
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Two-Dimensional MXene (Ti3C2Tx)-based Nano-Photosensitizers for Enhanced Photothermal Ablation of Tumor Cells
Available online: 25 October 2024More LessCancer remains one of the leading causes of death globally, accounting for approximately one in every six deaths. Traditional cancer therapies, including surgery, chemotherapy, chemoimmunotherapy, and radiation, face numerous challenges and limitations. In this context, we explore the advantages of photothermal therapy (PTT) using two-dimensional (2D) MXene-based nanocomposites for cancer treatment. MXenes, co Read More
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Guiding Therapeutics: Lipid Labyrinths and Nanostructures for Enhanced Drug Delivery
Authors: Swatantra K.S. Kushwaha, Shruti Khare and Amit MishraAvailable online: 11 October 2024More LessNanostructured lipid carriers (NLCs) offer a breakthrough platform for drug therapy, surpassing traditional limitations and delivering exceptional performance. Among various nanoparticulate systems, lipid nanoparticles stand out as one of the most promising options for medication delivery. NLCs stand out due to their solid matrix at ambient temperatures, setting them apart from conventional lipid-based carriers such as nan Read More
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In vitro Characterization and Drug Release Studies of Ethambutol-Loaded Nanoparticles for Pulmonary Delivery
Authors: Sonali Jayronia, Amrita Singh and Sudhanshu MishraAvailable online: 11 October 2024More LessBackground The development of more effective drug delivery techniques is necessary to increase treatment efficacy and patient compliance since tuberculosis (TB) is still a serious worldwide health concern. Ethambutol is a vital aspect of TB treatment, and using nanoparticles to carry it to the lungs may provide targeted delivery and prolonged release, which might enhance the effectiveness of the treatment. Objective This wor Read More
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