Current Organic Chemistry - Volume 20, Issue 27, 2016

The generation of perfluoroalkyl radicals (RF•) by means of photocatalysis is a more suitable route than the established methods employing chemical initiators, like azo or peroxide compounds or the use of transition metals. Conditions governed by photocatalysis can allow for a wide range of functional groups and, therefore, can be applied to the latestage transformation of bioactive molecules. Organic photocatalyst Read More

Five-membered ring products of cyclometalation reactions are utilized as dyesensitizers for manufacturing very stable dye-sensitized solar cells. Such solar cells have greater stability than standard chelate-type N719 solar cells because the cyclometalated ligands in the five-membered ring products are stronger donors than the thiocyanate groups in the standard type. Solar cells with high overall energy conversion efficienci Read More

During the last decades, indium chemistry has attracted considerable attentions from synthetic community and has found widespread applications in organic synthesis. Compared to many other commonly used metals (such as Li, Al, Mg, and Zn), indium is insensitive to water and air, allowing the operation of indium-mediated organic transformations in aqueous media. In addition, its mildness also permits indium-mediated rea Read More

In this study, we want to have an extensive overview on the application of triphosgene in organic synthesis. We begin with an introductory discussion of the nature of triphosgene, and introduce several procedures for the preparation of triphosgene. It holds an advantage over other similar reagents, such as phosgene and diphosgene, of being a safe and easy to handle solid. On the other hand, it is safer and more co Read More

At present, ionic liquids (ILs) are playing a more and more important role in organic synthesis as green catalysts and solvents. At the same time, researchers from both academia and industry have great interests in the related application of new ILs with unique structural features. Many neutral and acidic ionic liquids were used to catalyze condensation and esterification processes, which are two important reactions in fin Read More

Both carbonyl groups of a β-keto amide are highly activated by intramolecular hydrogen bonding. Hence, β-keto amides readily undergo amination, giving either β-aminobutenamides or N-substituted acetoacetamides. The chemoselectivity was influenced by the steric bulk of the keto amide or the amine: while amination at the ketone moiety predominated at low temperatures with less hindered substrates, amination at the ami Read More

In 1893, the synthesis of 3,4-dihydropyrimidin-2(1H)-ones via three-component condensation reaction of an aromatic aldehyde, urea and ethyl acetoacetate was reported for the first time by P. Biginelli. In the past century, such 3,4-dihydropyrimidin-2-(1H)-ones and related heterocyclic compounds have received a considerable amount of attention due to the interesting pharmacological properties associated with this het Read More

Nowadays, biodegradable polymers are attractive candidates to create highperformance and environmentally friendly catalytic species. Polymeric materials for catalytic processes must be biocompatible and preferably biodegradable. Sulfonic acid functionalized chitosan (CS-SO3H) was easily prepared by the reaction of chitosan with chlorosulfonic acid. CS-SO3H is found to catalyze the Hantzsch reaction to produce 1,4-dihydr Read More