Current Organic Chemistry - Volume 20, Issue 3, 2016

The goal of this review is to provide a comprehensive overview of the developments in enantioselective two- and multicomponent domino reactions as well as tandem sequences catalyzed by chiral nickel complexes, covering the literature since the beginning of 2004. Related to the lower costs of nickel catalysts in comparison with other transition metals, enantioselective nickel-catalyzed domino and sequential tandem processes h Read More

Fluorescent probes possess low limit, high sensitivity, and wide response range, etc. but they have some disadvantages including contamination to the detection system, limitation of repeated use. Polymers combined with fluorescent probes could overcome these drawbacks and they have been widely used in chemosensor, biological imaging and PH/temperature sensor for their unique favorable mechanical properties and good Read More

This review supplies the reader with a detailed overview on the utilization of intramolecular processes for a design and synthesis of prodrugs. It is well known that a respected number of drugs suffer from low bioavailability, toxicity, unpleasant taste and presystemic first-pass metabolism which result in drug inactivation. The classical prodrug approach in which the linkage attaching the parent drug to its non-toxic linker and cleav Read More

An efficient and convenient nanocrystalline MgO catalyzed one pot preparation of double Schiff bases via solvent free method is described. This protocol was designed through treatment of salicylaldehyde (or furfural) with various aromatic aldehydes and NH4OOCPh to afford double Schiff bases in high purity, excellent yields and short reaction times. These compounds are used as significant ligands that can be coordinated Read More