Current Organic Chemistry - Volume 20, Issue 20, 2016

The literature on the syntheses of substituted 1-(indol-3-yl)-1,2,3,4-tetrahydroisoquinoline derivatives is reviewed. Two main synthetic procedures have been applied for these syntheses. One is cross-dehydrogenative coupling, which can furnish various C-3 functionalized indoles; oxidants and/or catalysts are usually needed. Another convenient synthetic method is the aza-Friedel–Crafts alkylation of indole derivatives with dihydroi Read More

Graphene is an atomically thin, two-dimensional allotrope of carbon with excellent chemical, mechanical, and electronic properties. Recent studies have revealed that using graphene or modified graphene as a catalyst support or metal-free catalyst can result in significant improvement in the catalytic activity, selectivity, reusability and tolerance due to the unique structure of graphene. This review summarized the recent prog Read More

N,N-Dibromosulfonamides are unique reagents in organic synthesis and have been employed in several areas of application. They have demonstrated high reactivity in bromination reactions, vicinal bromoamine synthesis, in the construction of C-N bonds, and several other transformations. This review describes the scope and application of the N,Ndibromosulfonamides as bromine sources, as amine sources Read More

Phosphaalkenes and azaphospholes both have C=P- moiety; while the former is stabilized kinetically, the latter attains stability thermodynamically. A close examination of the synthesis, structures and reactivity of these two classes of phospha-organic compounds reveals that these compounds exhibit close analogy with their respective non-phospha analogues, namely alkenes and azoles. In this mini-review, the analogies betwee Read More

As the high-profile new environmental material, ionic liquid is widely used in various fields with its extraordinary performance. It can be used as a substitute of traditional functional material and it also provides a theoretical basis for research and development of new material. This paper introduced the applications of ionic liquid in physical, chemical and biological areas as lubricant, plasticizer, variable focus lenses, optical Read More

The reaction of variously N-substituted α-furanamides with singlet oxygen has been examined. In addition to the expected fragmentation products the reaction affords rearranged 5-hydroxy- and 5-aryloxy-2(5H)-furanones. Products distribution depends on diverse factors: the presence of α-hydrogen, the presence of the amidic group, the nature and the number of nitrogen substituents. The rearrangement to 5-aryloxy-2(5H) Read More

An efficient, atom-economical, four-component one-pot reaction method was developed for pyrano[2,3-c]pyrazole-3-carboxylates using dimethylacetylenedicarboxylate, hydrazine hydrate, malononitrile and aromatic aldehydes, using a RuCaHAp catalyst. Ten new substituted pyrano[2,3-c]pyrazole-3-carboxylate derivatives (5a-k) were synthesized in good to excellent yields (88 to 97%), at room temperature wi Read More