Current Organic Chemistry - Volume 19, Issue 22, 2015

In the rapidly developing areas of nanotechnology, nano-scale materials as heterogeneous catalysts in the synthesis of organic molecules have got more and more attentions. In this review, we will summarize the synthesis of a new type of ultrathin nanostructure via wet chemical method and several new catalytic applications to establish heterogeneous catalytic system in “green” environments. Further study shows that these Read More

Photochemistry has tremendous applications in the synthetic organic chemistry. The photochemical behaviors of compounds containing carbonyl chromophores are most widely and extensively investigated as these elicit many types of photochemical reactions. Of these, the photochemical intramolecular H-abstraction reactions are of great importance as these have been used as the suitable tools for the creation of the nu Read More

Corey-Fuchs olefination is a two-step reaction, involving the reaction of an aldehyde and tetrabromomethane (CBr4) in the presence of the triphenylphosphine (Ph3P) to synthesize 1,1-dibromoolefins. In the second step, the conversion of the dibromoolefins to alkynes occurred in the presence of n-BuLi as the base. This transformation was first discovered by E. J. Corey and P. L. Fuchs in 1972. Due to the importance of Read More

A purine nucleoside phosphorylase from Aeromonas hydrophila (AhPNP) was found to catalyze the regio- and stereoselective transfer of the ribofuranosyl moiety from 7-methylguanosine iodide (1) to a library of 6- substituted purines, resulting in moderate to high conversions (18-65%) into their ribonucleoside counterparts (26- 34, 36-49). Exploring of substrate recognition by AhPNP with regard to 6-position of purine ba Read More